Calleja Duran Ignacio, Hernandez Sanchez Jose Emilio, Popescu Oana Beatrice
Department of Urology, Hospital Universitario General de Villalba, Collado Villalba, Madrid, Spain.
J Med Cases. 2025 Aug 22;16(8):287-292. doi: 10.14740/jmc5145. eCollection 2025 Aug.
Bladder paraganglioma accounts for < 0.05% of all bladder tumors, and very few cases have been reported to date. Because clinical and radiological findings are often nonspecific, many lesions are misdiagnosed until surgery, exposing patients to preventable perioperative catecholamine crises. We report an unusual case of a 77-year-old woman, in whom a 17-mm bladder paraganglioma was discovered incidentally during imaging for suspected Crohn's disease. The patient was entirely asymptomatic and had normal catecholamine levels. Transurethral resection of the bladder (TURB) achieved complete excision, and no recurrence was detected at 6-month follow-up. This case illustrates that bladder paraganglioma can occur outside the typical age range and without adrenergic symptoms, emphasizing the need to consider this entity in the differential diagnosis of any well-circumscribed, hypervascular bladder mass. Early recognition enables appropriate perioperative planning and long-term multidisciplinary surveillance. We discuss the tumor's characteristics, management, and the importance of long-term surveillance.
膀胱副神经节瘤占所有膀胱肿瘤的比例不到0.05%，迄今为止报道的病例非常少。由于临床和影像学表现往往不具有特异性，许多病变在手术前被误诊，使患者面临可预防的围手术期儿茶酚胺危机。我们报告了一例不寻常的病例，一名77岁女性，在因疑似克罗恩病进行影像学检查时偶然发现了一个17毫米的膀胱副神经节瘤。患者完全无症状，儿茶酚胺水平正常。经尿道膀胱肿瘤切除术（TURB）实现了完全切除，6个月随访未发现复发。该病例表明，膀胱副神经节瘤可发生在典型年龄范围之外且无肾上腺素能症状，强调在鉴别诊断任何边界清晰、血运丰富的膀胱肿块时需要考虑这一实体。早期识别有助于进行适当的围手术期规划和长期多学科监测。我们讨论了该肿瘤的特征、治疗及长期监测的重要性。
