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血流动力学稳定的主动脉瘤破裂患者手术延迟:一项多中心回顾性分析。

Delay in Surgery for Ruptured Aortic Aneurysm in Hemodynamically Stable Patients: A Multicenter Retrospective Analysis.

作者信息

Kawahigashi Teiko, Taisuke Jo, Shimizu Taro, Isogai Naoko, Ogino Hidemitsu, Takagi Toshio, Watanabe Kazunao, Yasunaga Hideo, Kawachi Jun

机构信息

Department of General Internal Medicine, Shonan Kamakura General Hospital, Kamakura, JPN.

Department of Emergency Medicine, Tokyo Nishi Tokushukai Hospital, Tokyo, JPN.

出版信息

Cureus. 2025 Aug 3;17(8):e89294. doi: 10.7759/cureus.89294. eCollection 2025 Aug.

Abstract

INTRODUCTION

Thoracic aortic aneurysm or abdominal aortic aneurysm (TAA/AAA) is a fatal surgical emergency, and time to surgery can be a key factor in improving survival outcomes in patients. In this study, we examined the association between systolic blood pressure on arrival and door-to-surgery time in patients with ruptured TAA/AAA, hypothesizing that patients with ruptured thoracic or abdominal aortic aneurysms without hypotension may have longer door-to-surgery times than those with hypotension.

METHODS

This retrospective study was conducted at two community hospitals, Shonan Kamakura General Hospital and Tokyo Nishi Tokushukai Hospital, in Japan, and included patients with ruptured thoracic or abdominal aortic aneurysms who were admitted to these hospitals from 2010 to 2021. Door-to-surgery time was compared between patients with stable blood pressure (>90 mmHg) and those with hypotension (≤90 mmHg) using multivariable linear regression.

RESULTS

Among 94 patients (median age 82 years), 29.8% were in hypotension on arrival. Hemodynamically stable patients had a longer door-to-surgery time than those with hypotension (152 vs. 95.5 min, p = 0.003). Multivariable analysis showed significantly shorter door-to-surgery times for patients with hypotension (percent difference, -26.3%; 95% CI, -48.7% to -4.0%).

CONCLUSION

Hemodynamically stable patients with ruptured TAA/AAA can have longer door-to-surgery times, leading to avoidable delays in successful treatment. This study underscores the need for heightened clinical vigilance among physicians, as a delay in treatment may lead to worse outcomes in these patients.

摘要

引言

胸主动脉瘤或腹主动脉瘤(TAA/AAA)是一种致命的外科急症,手术时机可能是改善患者生存结局的关键因素。在本研究中,我们调查了TAA/AAA破裂患者到达时的收缩压与门到手术时间之间的关联,假设无低血压的胸主动脉或腹主动脉瘤破裂患者的门到手术时间可能比有低血压的患者更长。

方法

这项回顾性研究在日本的两家社区医院——湘南镰仓综合医院和东京西独协医院进行,纳入了2010年至2021年期间入住这些医院的胸主动脉或腹主动脉瘤破裂患者。使用多变量线性回归比较血压稳定(>90 mmHg)和低血压(≤90 mmHg)患者的门到手术时间。

结果

在94例患者(中位年龄82岁)中,29.8%到达时处于低血压状态。血流动力学稳定的患者门到手术时间比低血压患者更长(152分钟对95.5分钟,p = 0.003)。多变量分析显示,低血压患者的门到手术时间显著缩短(差异百分比,-26.3%;95%CI,-48.7%至-4.0%)。

结论

TAA/AAA破裂且血流动力学稳定的患者可能有更长的门到手术时间,导致成功治疗出现可避免的延迟。本研究强调医生需要提高临床警惕性,因为治疗延迟可能导致这些患者出现更差的结局。

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