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性别焦虑症成年患者合法性别变更后的稳定性

Stability After Legal Gender Change Among Adults With Gender Dysphoria.

作者信息

Clark Kristen D, White Richard A, Karamanis Georgios, Indremo Malin, Özel Fatih, Skalkidou Alkistis, Frisell Thomas, Papadopoulos Fotios C

机构信息

Department of Medical Sciences, Clinical Psychiatry, Uppsala University, Uppsala, Sweden.

Norwegian Institute of Public Health, Oslo, Norway.

出版信息

JAMA Netw Open. 2025 Sep 2;8(9):e2527780. doi: 10.1001/jamanetworkopen.2025.27780.

Abstract

IMPORTANCE

The number of people seeking treatment for gender dysphoria (GD) has risen in recent decades, yet data remain limited for understanding cases of detransition (ie, the reversal of social, medical, or legal transition). Legal gender change in national registers poses an opportunity to examine legal gender reversals, which may reflect an aspect of the detransition process, while also informing an understanding of the stability after a legal gender change.

OBJECTIVE

To determine the probability of obtaining a legal gender change and its stability over time among people diagnosed with GD in Sweden during a 10-year study period.

DESIGN, SETTING, AND PARTICIPANTS: In this population cohort study using data from Swedish national registers from January 1, 2013, to December 31, 2023, individuals who received their first International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10), diagnosis code for GD during the study period were included. While participants may have received a GD ICD-10 code as youths, legal gender changes only occurred for adults (aged ≥18 years) based on legal requirements during the time of data collection.

EXPOSURE

Gender dysphoria.

MAIN OUTCOMES AND MEASURES

Legal gender change and its stability, that is, absence of legal gender reversal, as reported in the registry. Kaplan-Meier survival analysis was used to determine the probability of legal gender change and its stability during a 10-year study period.

RESULTS

A total of 7293 people with a GD diagnosis were included (36 025 person-years). Approximately one-third of the sample (n = 2467) obtained a legal gender change during the study period. The probability of legal gender change at 10 years following diagnosis was 58.3% (95% CI, 56.2%-60.4%). Twenty-one cases of legal gender reversal were identified. The probability of legal gender stability at 10 years following the initial change was 97.7% (95% CI, 96.3%-99.2%), with no differences by sex assigned at birth for either outcome.

CONCLUSIONS AND RELEVANCE

In this cohort study using national population registry data, a significant proportion of participants with GD in Sweden obtained legal gender change within 10 years of follow-up. Despite significant growth of the population with GD, the probability of legal gender stability during the 10-year study period was high, at almost 98%. These results highlight that legal gender reversal was an infrequent occurrence in a national sample.

摘要

重要性

近几十年来,寻求性别焦虑症(GD)治疗的人数有所增加,但对于了解性别转变逆转(即社会、医疗或法律转变的逆转)的案例,数据仍然有限。国家登记册中的法定性别变更为研究法定性别逆转提供了一个机会,这可能反映了性别转变逆转过程的一个方面,同时也有助于理解法定性别变更后的稳定性。

目的

确定在瑞典10年研究期间被诊断为GD的人群中获得法定性别变更的概率及其随时间的稳定性。

设计、背景和参与者:在这项队列研究中,使用了瑞典国家登记册从2013年1月1日至2023年12月31日的数据,纳入了在研究期间首次获得第十次修订的《国际疾病和相关健康问题统计分类》(ICD-10)中GD诊断代码的个体。虽然参与者在年轻时可能获得了GD的ICD-10代码,但根据数据收集时的法律要求,法定性别变更仅发生在成年人(年龄≥18岁)中。

暴露因素

性别焦虑症。

主要结局和测量指标

登记册中报告的法定性别变更及其稳定性,即不存在法定性别逆转。采用Kaplan-Meier生存分析来确定10年研究期间法定性别变更的概率及其稳定性。

结果

共纳入7293名诊断为GD的人(36025人年)。在研究期间,约三分之一的样本(n = 2467)获得了法定性别变更。诊断后10年法定性别变更的概率为58.3%(95%CI,56.2%-60.4%)。确定了21例法定性别逆转案例。初始变更后10年法定性别稳定的概率为97.7%(95%CI,96.3%-99.2%),两种结局在出生时指定的性别方面均无差异。

结论和相关性

在这项使用国家人口登记数据的队列研究中,瑞典很大一部分被诊断为GD的参与者在随访的10年内获得了法定性别变更。尽管患有GD的人群显著增加,但在10年研究期间法定性别稳定的概率很高,几乎达到98%。这些结果表明,在全国样本中,法定性别逆转是很少见的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ec0/12411971/a5d29a3c242b/jamanetwopen-e2527780-g001.jpg

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