Fernell E, von Wendt L, Serlo W, Heikkinen E, Andersson H
Z Kinderchir. 1985 Dec;40 Suppl 1:12-4. doi: 10.1055/s-2008-1059758.
The data on all 881 primary or revision shunt operations performed on 158 paediatric patients treated in Gothenburg, Sweden from 1967 to 1984 and 101 patients treated in Oulu, Finland from 1968 to 1983 were pooled for the purpose of comparative evaluation of the function of ventriculoatrial (VA) and ventriculoperitoneal (VP) shunts. Ventriculoperitoneal shunting was the method of choice in Gothenburg and ventriculoatrial shunting in Oulu. The results of the 723 operations (305 VA and 418 VP shunts) were evaluated as the other 158 operations were for ventriculostomas, shunt removals and other procedures. 80 children had exclusively VA shunts and 133 children had exclusively VP shunts. Irrespective of the method of analysis the VP shunts were more frequently infected. The estimated relative risk for obstruction of the shunt (Meyer-Kaplan method) was shown to be significantly higher in VA shunts, but only at a low level of statistical significance (p less than 0.1). All other shunt complications were distributed uniformly in both groups. There was, however, a trend towards a higher mortality among children with exclusively VA shunts. Therefore it was concluded that despite the higher risk for infection in VP shunts, these still should be considered a safer choice, as the complications of VA shunts present greater risks.
为了比较评估脑室心房(VA)分流术和脑室腹腔(VP)分流术的功能,我们汇总了1967年至1984年在瑞典哥德堡接受治疗的158名儿科患者以及1968年至1983年在芬兰奥卢接受治疗的101名儿科患者所进行的全部881例初次或翻修分流手术的数据。脑室腹腔分流术是哥德堡的首选方法,而脑室心房分流术是奥卢的首选方法。由于另外158例手术是脑室造口术、分流管移除术和其他手术,因此我们对723例手术(305例VA分流术和418例VP分流术)的结果进行了评估。80名儿童仅接受了VA分流术,133名儿童仅接受了VP分流术。无论采用何种分析方法,VP分流术感染的频率都更高。采用Meyer-Kaplan方法估计,VA分流术的分流管阻塞相对风险显著更高,但统计学显著性水平较低(p<0.1)。两组中所有其他分流并发症的分布均一。然而,仅接受VA分流术的儿童死亡率有升高的趋势。因此得出结论,尽管VP分流术感染风险更高,但仍应被视为更安全的选择,因为VA分流术的并发症风险更大。