Serlo W, Fernell E, Heikkinen E, Anderson H, von Wendt L
Department of Paediatrics, University of Oulu, Finland.
Childs Nerv Syst. 1990 Mar;6(2):92-4. doi: 10.1007/BF00307928.
Shunt function and complications in different etiologies of childhood hydrocephalus were studied in a series of 306 patients involving 1102 shunt operations. Shunts in patients with hydrocephalus caused by neoplasms proved to be most prone to shunt complications. The patency time for shunts in these patients was significantly shorter than for shunts in other patient categories [Standard number of deviations (SND) 5.9; P less than 0.001, Meyer-Kaplan life table analysis]. When the two main groups of infantile hydrocephalus-congenital obstructive hydrocephalus and hydrocephalus caused by perinatal intracerebral hemorrhage-were compared, the latter group proved to be significantly more prone to shunt infections (P less than 0.01), with an infection rate of 17.8% compared with 8.9% for the former group. The importance of this fact is stressed by the observation that these patients appear to constitute an increasing percentage of hydrocephalic patients. According to the present study, patients with congenital intracranial cysts and hydrocephalus are less prone to shunt complications, i.e., the infection rate is 6.8%, which is significantly less than that of patients with other types of hydrocephalus (P less than 0.01; chi-square test).
在涉及1102次分流手术的306例儿童脑积水患者中，研究了不同病因儿童脑积水的分流功能及并发症。结果表明，肿瘤所致脑积水患者的分流最易发生并发症。这些患者分流管的通畅时间明显短于其他类型患者的分流管[标准偏差数（SND）5.9；P<0.001，Meyer-Kaplan寿命表分析]。比较婴儿脑积水的两大主要类型——先天性梗阻性脑积水和围生期脑内出血所致脑积水，发现后一组明显更易发生分流感染（P<0.01），感染率为17.8%，而前一组为8.9%。鉴于这些患者在脑积水患者中所占比例似乎越来越大，这一事实的重要性值得强调。根据本研究，先天性颅内囊肿合并脑积水的患者较少发生分流并发症，即感染率为6.8%，明显低于其他类型脑积水患者（P<0.01；卡方检验）。
