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脑脊液免疫球蛋白在脑蛛网膜炎中的诊断价值

[Diagnostic value of spinal fluid immunoglobulins in cerebral arachnoiditis].

作者信息

Khil'ko V A, Usanov E I, Khlunovskiĭ A N, Umerov E Kh, Paskhina M N

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1985;85(12):1789-92.

PMID:4090835
Abstract

The authors believe that the deficiency of immunoglobulins A in the cerebrospinal fluid (CSF) of patients with arachnoiditis may be explained by an increase in their consumption due to antigenic aggression in relation to the meninges, which results in extremely low values of the circulating immunoglobulins A. The absence of immunoglobulins A in the CSF of patients with cerebral arachnoiditis is one of the components of its pathogenesis owing to impairment of permeability of the blood brain barrier and fixation of antigens in the tissues of the brain and meninges.

摘要

作者认为,蛛网膜炎患者脑脊液(CSF)中免疫球蛋白A的缺乏可能是由于与脑膜的抗原侵袭导致其消耗增加所致,这导致循环免疫球蛋白A的值极低。脑蛛网膜炎患者脑脊液中缺乏免疫球蛋白A是其发病机制的组成部分之一,原因是血脑屏障通透性受损以及抗原在脑和脑膜组织中的固定。

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