Akimov G A, Komandenko N I, Zinchenko V A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(5):682-4.
Measurement of activity of gamma-glutamyl transferase (GGTF) in the cerebrospinal fluid (CSF) revealed a sharp elevation in the cytosis and activity of GGTF in the ventricular portion of the CSF, which points to dystrophic changes in nerve cells and damage of their membranes and, consequently, to an increase in the permeability of the blood-brain barrier. Determination of GGTF activity in the CSF may be recommended as a supplemental method of the differential diagnosis of cerebral meningites.
对脑脊液(CSF)中γ-谷氨酰转移酶(GGTF)活性的测量显示,CSF脑室部分的细胞增多和GGTF活性急剧升高,这表明神经细胞发生营养不良性变化及其膜受损,进而导致血脑屏障通透性增加。脑脊液中GGTF活性的测定可作为鉴别诊断脑膜脑炎的补充方法。