Fidalgo Alejandro Pérez, Alonso Pilar, Andión Maitane, Cañete Adela, Collado Erica, Colino Carmen Garrido, Codina José Gómez, Carrasco Xavier Díaz, Sanz Ramón García, Expósito Sergio Hernández, Lopez-Fernandez Teresa, Medin Gabriela, Molinés Antonio, Vega Alberto Moreno, Ramos Mónica, Miguel Iñigo San, García Joaquín Sánchez, Santolaya Fátima
Department of Oncology and Hematology, INCLIVA Biomedical Research Institute, Valencia, Spain.
Spanish Society of Medical Oncology (SEOM), Hospital Clínico Universitario de Valencia, Madrid, Spain.
Clin Transl Oncol. 2025 Sep 4. doi: 10.1007/s12094-025-04047-0.
Adolescent and young adult cancer survivors (AYACS) represent a specific cancer patient population with unique chronic health issues difficult to identify in early, reversible phases with standard monitoring protocols. This review, conducted by a group of Spanish experts, provides recommendations for managing AYACS, focusing on key areas, such as cardiac toxicities, neurotoxicity and neurocognitive disorders, metabolic syndrome, secondary primary malignancies, bone toxicities, sexuality and fertility, psychosocial aspects, and other treatment-related toxicities.
青少年及年轻成人癌症幸存者（AYACS）是一类特殊的癌症患者群体，他们存在独特的慢性健康问题，采用标准监测方案在早期可逆阶段难以识别。由一群西班牙专家开展的本综述为管理AYACS提供了建议，重点关注心脏毒性、神经毒性和神经认知障碍、代谢综合征、继发原发性恶性肿瘤、骨骼毒性、性与生育、心理社会方面以及其他与治疗相关的毒性等关键领域。
