Wilailak Sarikapan, Kengsakul Malika, Kehoe Sean
Department of Obstetrics and Gynecology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Department of Obstetrics and Gynecology, Panyananthaphikkhu Chonprathan Medical Center, Srinakharinwirot University, Nonthaburi, Thailand.
Int J Gynaecol Obstet. 2025 Sep;171 Suppl 1:120-128. doi: 10.1002/ijgo.70276.
Cervical cancer remains a major health burden, particularly in low- and middle-income countries, despite being one of the most preventable cancers. WHO's 90-70-90 targets aim to eliminate cervical cancer globally by 2030. These targets include 90% of girls fully vaccinated with the HPV vaccine by the age of 15 years, 70% of women screened using a high-performance test by the age of 35 years and again by 45 years, and 90% of women with cervical disease receiving appropriate treatment. Achieving these goals requires coordinated national efforts to strengthen health systems, ensure equitable access to care, and integrate cervical cancer control into broader health policies. This review outlines key strategic approaches, including the transition from conventional screening methods to HPV-based screening, the adoption of innovative triage techniques, the implementation of single-dose HPV vaccination, and the integration of primary treatment with palliative care. The strategy places strong emphasis on addressing health inequities, enhancing monitoring systems, and fostering partnerships between governments, non-governmental organizations, and the private sector. With concerted global and national action, the elimination of cervical cancer is not only a possibility but an imminent reality.
宫颈癌仍然是一项重大的健康负担，尤其是在低收入和中等收入国家，尽管它是最可预防的癌症之一。世界卫生组织的90-70-90目标旨在到2030年在全球消除宫颈癌。这些目标包括90%的女孩在15岁前完全接种人乳头瘤病毒（HPV）疫苗，70%的女性在35岁时使用高效检测方法进行筛查，并在45岁时再次筛查，以及90%患有宫颈疾病的女性接受适当治疗。实现这些目标需要国家作出协调一致的努力，以加强卫生系统，确保公平获得医疗服务，并将宫颈癌控制纳入更广泛的卫生政策。本综述概述了关键的战略方法，包括从传统筛查方法向基于HPV的筛查过渡、采用创新的分流技术、实施单剂量HPV疫苗接种，以及将初级治疗与姑息治疗相结合。该战略高度重视解决卫生不公平问题、加强监测系统以及促进政府间、非政府组织和私营部门之间的伙伴关系。通过全球和国家的协同行动，消除宫颈癌不仅是可能的，而且即将成为现实。
