Jalil Ahmad, Rajab Fatima, Zaidi Maheen
Internal Medicine, Baptist Memorial Hospital-North Mississippi, Oxford, USA.
Internal Medicine, King Edward Medical University, Lahore, PAK.
Cureus. 2025 Aug 4;17(8):e89322. doi: 10.7759/cureus.89322. eCollection 2025 Aug.
Fulminant myocarditis is a rare but life-threatening complication of influenza A infection that can result in acute biventricular failure leading to cardiogenic shock. Here, we present the case of a young patient who developed acute bilateral heart failure secondary to influenza A and was successfully stabilized using both right and left-sided Impella devices. This case highlights the critical role of early and aggressive mechanical circulatory support (MCS) in managing fulminant myocarditis and emphasizes the utility of Impella in cases of severe cardiac dysfunction. Our patient showed a remarkable recovery, with significant improvement in ejection fraction within days of initiating MCS. Notably, a strong family history of myocarditis was present, raising the possibility of a genetic predisposition to developing fulminant myocarditis in response to viral infections. This case underscores the potential for serious and potentially fatal cardiogenic complications of a common viral illness in genetically susceptible individuals.
暴发性心肌炎是甲型流感感染罕见但危及生命的并发症,可导致急性双心室衰竭,进而引发心源性休克。在此,我们报告一例年轻患者,该患者继发于甲型流感后出现急性双侧心力衰竭,并通过使用左右两侧的Impella装置成功实现病情稳定。本病例突出了早期积极的机械循环支持(MCS)在暴发性心肌炎治疗中的关键作用,并强调了Impella在严重心功能不全病例中的实用性。我们的患者恢复显著,在启动MCS数天内心脏射血分数有显著改善。值得注意的是,患者有明显的心肌炎家族史,提示存在因病毒感染而发生暴发性心肌炎的遗传易感性。本病例强调了在遗传易感性个体中,常见病毒性疾病可能引发严重且潜在致命的心源性并发症。