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缝线失效时:同一患者体内 Inspire 装置和髋关节假体的挤出

When Sutures Fail: Extrusion of an Inspire Device and a Hip Prosthesis in the Same Patient.

作者信息

Sorenson Kalin R, Robins Cameron, Verigan Keala, Gerber Nicholas, Musso Louis

机构信息

Otolaryngology, Rocky Vista University College of Osteopathic Medicine, Ivins, USA.

Surgery, Rocky Vista University College of Osteopathic Medicine, Ivins, USA.

出版信息

Cureus. 2025 Aug 3;17(8):e89280. doi: 10.7759/cureus.89280. eCollection 2025 Aug.

Abstract

Implant extrusion is a rare but serious complication typically linked to infection, poor wound healing, or material intolerance. This case report describes a 79-year-old female patient who experienced extrusion of both a hip prosthesis and an Inspire hypoglossal nerve stimulator (Inspire Medical Systems, Inc., Minnesota, USA), each event associated with the use of Ethibond (Ethicon, Johnson & Johnson, Georgia, USA) sutures. The patient had a history of obstructive sleep apnea refractory to continuous positive airway pressure (CPAP) therapy and underwent Inspire device implantation. Postoperatively, she developed a sterile fluid collection and wound dehiscence, leading to visible extrusion of the device. Notably, she had previously experienced a near extrusion of a hip prosthesis, also linked to Ethibond. In both cases, the infectious workup was negative. Following explantation and reimplantation of the Inspire device using Monocryl and Prolene sutures (both by Ethicon, Johnson & Johnson, Georgia, USA) and the application of a dermal graft, the patient achieved successful healing without recurrence. This case underscores the importance of considering suture-related foreign body reactions in patients with recurrent implant extrusion and no evidence of infection. Surgeons should remain vigilant in selecting suture materials, especially in patients with a history of adverse reactions, and future research should explore suture-tissue interactions to guide safer implant practices.

摘要

植入物外露是一种罕见但严重的并发症,通常与感染、伤口愈合不良或材料不耐受有关。本病例报告描述了一名79岁女性患者,其髋关节假体和Inspire舌下神经刺激器(美国明尼苏达州Inspire Medical Systems公司)均发生了外露,每一次事件都与使用Ethibond缝线(美国佐治亚州强生公司Ethicon生产)有关。该患者有阻塞性睡眠呼吸暂停病史,对持续气道正压通气(CPAP)治疗无效,接受了Inspire装置植入。术后,她出现了无菌性积液和伤口裂开,导致装置明显外露。值得注意的是,她之前曾经历过一次髋关节假体近乎外露的情况,也与Ethibond有关。在这两例中,感染检查均为阴性。在使用Monocryl和Prolene缝线(均由美国佐治亚州强生公司Ethicon生产)取出并重新植入Inspire装置以及应用皮肤移植后,患者成功愈合且未复发。本病例强调了在植入物反复外露且无感染证据的患者中考虑缝线相关异物反应的重要性。外科医生在选择缝线材料时应保持警惕,尤其是有不良反应史的患者,未来的研究应探索缝线与组织的相互作用,以指导更安全的植入操作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bac6/12405961/46eaedc3b245/cureus-0017-00000089280-i01.jpg

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