Matsuda Masakazu, Yoshiya Shohei, Kawada Ippei, Nakamura Sota, Tada Kazuhiro, Ito Kensaku, Koso Hidenori, Kuroda Yosuke, Yoshizumi Fumitaka, Iwaki Kentaro, Hiroshige Shoji, Yamashita Yo-Ichi, Takeuchi Hideya, Yoshizumi Tomoharu, Fukuzawa Kengo
Department of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka-shi, Fukuoka 812-8582, Japan.
J Surg Case Rep. 2025 Sep 3;2025(9):rjaf679. doi: 10.1093/jscr/rjaf679. eCollection 2025 Sep.
Hematogenous metastases of hepatocellular carcinoma (HCC) to the small intestine are rare. In most cases, hematogenous metastasis is symptomatic, including perforation or bleeding, and the prognosis is poor. A 63-year-old man had lower right abdominal pain, and small intestinal obstruction due to chronic inflammation of the foreign body was suspected on computed tomography. Blood tests revealed elevated alpha-fetoprotein (AFP). He had undergone four surgeries for HCC. Conservative treatment was administered, but there was little improvement. A segmental resection of the small intestine was performed. A type 2 tumor was found in the resected specimen, and pathological examination led to a diagnosis of HCC metastasis in the small intestine. He survived without recurrence for 10 months after surgery. When a patient with a history of HCC treatment develops intestinal obstruction or intussusception, it is necessary to consider the possibility of small intestinal metastasis, especially if there is an increase in AFP.
肝细胞癌(HCC)血行转移至小肠较为罕见。在大多数情况下,血行转移有症状,包括穿孔或出血,且预后较差。一名63岁男性出现右下腹疼痛,计算机断层扫描怀疑因异物慢性炎症导致小肠梗阻。血液检查显示甲胎蛋白(AFP)升高。他曾因HCC接受过四次手术。给予了保守治疗,但改善甚微。遂进行了小肠节段性切除。在切除标本中发现了2型肿瘤,病理检查诊断为小肠HCC转移。术后他存活了10个月且无复发。有HCC治疗史的患者发生肠梗阻或肠套叠时,有必要考虑小肠转移的可能性,尤其是在AFP升高的情况下。