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An update on extracellular vesicles in hematologic disorders: molecular mediators, clinical biomarkers, and emerging therapeutics.

作者信息

Song Chunlei, Noormohamadi Hanieh, Soleimani Samarkhazan Hamed, Pilehvari Niloofar, Jafari Zahra, Maleknia Mohsen, Taghinejad Zahra, Kheyrandish Setare

机构信息

Outpatient department, affiliated hospital of Beihua University, Jilin, 132011, Jilin, China.

Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Mol Biol Rep. 2025 Sep 5;52(1):868. doi: 10.1007/s11033-025-10971-9.

DOI:10.1007/s11033-025-10971-9
PMID:40911103
Abstract
摘要

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本文引用的文献

1
Extracellular vesicles from chronic lymphocytic leukemia cells promote leukemia aggressiveness by inducing the differentiation of monocytes into nurse-like cells via an RNA-dependent mechanism.慢性淋巴细胞白血病细胞来源的细胞外囊泡通过RNA依赖机制诱导单核细胞分化为类滋养细胞，从而促进白血病的侵袭性。
Hemasphere. 2025 Jan 16;9(1):e70068. doi: 10.1002/hem3.70068. eCollection 2025 Jan.
2
CD98hc promotes drug resistance in extranodal natural killer/T cell lymphoma through tumor cell-derived small extracellular vesicles.CD98hc 通过肿瘤细胞来源的小细胞外囊泡促进结外自然杀伤/T 细胞淋巴瘤的耐药性。
Sci Signal. 2024 Sep 10;17(853):eadf9388. doi: 10.1126/scisignal.adf9388.
3
Insight into endothelial cell-derived extracellular vesicles in cardiovascular disease: Molecular mechanisms and clinical implications.
内皮细胞衍生细胞外囊泡与心血管疾病：分子机制与临床意义
Pharmacol Res. 2024 Sep;207:107309. doi: 10.1016/j.phrs.2024.107309. Epub 2024 Jul 14.
4
The impact of exosomes derived from B-cell acute lymphoblastic leukemia as a growth factor on bone marrow mesenchymal stromal cells.B 细胞急性淋巴细胞白血病衍生的外泌体作为生长因子对骨髓间充质基质细胞的影响。
Mol Biol Rep. 2024 Jun 14;51(1):749. doi: 10.1007/s11033-024-09674-4.
5
Extracellular vesicles in the Chronic Myeloid Leukemia scenario: an update about the shuttling of disease markers and therapeutic molecules.慢性髓性白血病中的细胞外囊泡：疾病标志物与治疗分子转运的最新进展
Front Oncol. 2024 Jan 8;13:1239042. doi: 10.3389/fonc.2023.1239042. eCollection 2023.
6
Environmental and Genetic Traffic in the Journey from Sperm to Offspring.从精子到后代的环境与遗传影响。
Biomolecules. 2023 Dec 7;13(12):1759. doi: 10.3390/biom13121759.
7
Impaired immunosuppressive effect of bone marrow mesenchymal stem cell-derived exosomes on T cells in aplastic anemia.骨髓间充质干细胞来源的外泌体对再生障碍性贫血 T 细胞免疫抑制作用的损害。
Stem Cell Res Ther. 2023 Oct 4;14(1):285. doi: 10.1186/s13287-023-03496-0.
8
Extracellular Vesicles in Chronic Lymphocytic Leukemia: Tumor Microenvironment Messengers as a Basis for New Targeted Therapies?慢性淋巴细胞白血病中的细胞外囊泡：作为新型靶向治疗基础的肿瘤微环境信使？
Cancers (Basel). 2023 Apr 14;15(8):2307. doi: 10.3390/cancers15082307.
9
Recent advances in the roles of exosomal microRNAs (exomiRs) in hematologic neoplasms: pathogenesis, diagnosis, and treatment.外泌体 microRNAs（exomiRs）在血液系统恶性肿瘤中的作用的最新进展：发病机制、诊断和治疗。
Cell Commun Signal. 2023 May 1;21(1):88. doi: 10.1186/s12964-023-01102-7.
10
Establishing 20S Proteasome Genetic, Translational and Post-Translational Status from Precious Biological and Patient Samples with Top-Down MS.利用自上而下的 MS 技术从珍贵的生物和患者样本中建立 20S 蛋白酶体的遗传、翻译后和翻译后状态。
Cells. 2023 Mar 8;12(6):844. doi: 10.3390/cells12060844.