Okada K, Hoshino H, Nakajima N, Kawashima T, Miyakita H, Nishizawa K, Shiramizu M, Nagata Y, Katsuoka Y, Kinoshita H
Hinyokika Kiyo. 1985 Oct;31(10):1727-42.
The following results were obtained from the statistical studies and drug sensitivity tests of bacterial florae isolated from the urinary tract in 1981 and 1982. Of the 2,029 strains isolated from out-patients, 627 (30.9%) were gram positive cocci, 24.1% were E. coli, 9.4% were Proteus spp., 9.2% were Enterococci, 8.9% were S. epidermidis, 7.0 % were K. pneumoniae, 5.7% were P. aeruginosa and the rest were others. Of the 754 strains isolated from hospitalized patients, 276 (36.6%) were gram positive cocci, 16.8% were Enterococci, 11.4% were S. epidermidis, 11.1% were P. aeruginosa, 8.8% were Proteus spp, 7.2% were E.coli, 6.5% were K.pneumoniae and the rest were others. The number of Proteus spp., P. aeruginosa and Enterococci detected in the isolates from the out-patients and that of E.coli, K. pneumoniae and Proteus spp., detected in the isolates from the in-patients were smaller than in previous reports. More non-fermentative gram-negative bacilli and S. epidermidis were detected in the isolates from both patients were than in previous years. The major isolates i.e., 9 species, from out-patients were more susceptible to the antimicrobial agents tested. The susceptibility of TC and SBPC to major isolates was lower than in previous years. During the past two years, we have been routinely using on inpatients the so-called third generation cefem antibiotics to treat urinary tract infections. This might be why the number of isolates of gram positive cocci has increased especially isolates from inpatients.
以下结果来自于1981年和1982年从泌尿道分离出的细菌菌群的统计研究和药敏试验。在从门诊患者中分离出的2029株菌株中，627株（30.9%）为革兰氏阳性球菌，24.1%为大肠杆菌，9.4%为变形杆菌属，9.2%为肠球菌，8.9%为表皮葡萄球菌，7.0%为肺炎克雷伯菌，5.7%为铜绿假单胞菌，其余为其他菌。在从住院患者中分离出的754株菌株中，276株（36.6%）为革兰氏阳性球菌，16.8%为肠球菌，11.4%为表皮葡萄球菌，11.1%为铜绿假单胞菌，8.8%为变形杆菌属，7.2%为大肠杆菌，6.5%为肺炎克雷伯菌，其余为其他菌。在门诊患者分离株中检测到的变形杆菌属、铜绿假单胞菌和肠球菌的数量，以及在住院患者分离株中检测到的大肠杆菌、肺炎克雷伯菌和变形杆菌属的数量均低于以往报告。在这两类患者的分离株中检测到的非发酵革兰氏阴性杆菌和表皮葡萄球菌比往年更多。门诊患者的主要分离株，即9种菌，对所测试的抗菌药物更敏感。头孢噻吩和头孢哌酮对主要分离株的敏感性低于往年。在过去两年中，我们一直在住院患者中常规使用所谓的第三代头孢菌素抗生素来治疗尿路感染。这可能就是革兰氏阳性球菌分离株数量增加的原因，尤其是住院患者的分离株。
