Li Lijing, Yang Tingzhong, Peng Sihui, Cottrell Randall R
Department of Obstetrics and Gynecology, Yongkang Women and Children's Health Hospital, Yongkang, China.
Maternal and Child Healthcare Service Department, Yongkang Women and Children's Health Hospital, Yongkang, China.
JMIR Form Res. 2025 Sep 5;9:e74370. doi: 10.2196/74370.
To mitigate the rapid spread of COVID-19, numerous countries have adopted lockdowns and quarantine measures. Despite their public health benefits, the effects of these measures on suicidal ideation have not been well documented.
This study aims to examine the relationship among COVID-19 infection, perceived beliefs, uncertainty stress, and suicidal ideation during the transition from quarantine to post-quarantine periods amid China's COVID-19 surge.
A prospective longitudinal observational design was used. Changing trends across the 6 time points were assessed using the Mann-Kendall test and the Cochran-Armitage test. A generalized estimating equation was used to analyze the associations between independent variables and suicidal ideation.
A total of 221 (96.5%) participants completed all 6 observation waves. The prevalence of suicidal ideation during the quarantine period was 16.7% (n=37), 14.5% (n=32), and 14.5% (n=32), while during the post-quarantine period, it was 13.8% (n=30), 10.9% (n=24), and 10.0% (n=22), respectively. A significant downward trend in suicidal ideation was observed. In contrast, perceived risk, perceived severity, and the number of new infections exhibited significant upward trends (z scores of 9.56, 7.13, and 3.69, respectively; P<.001, P<.001 and P=.002, respectively). However, uncertainty stress remained stable over time (z=0.71; P=.48). The generalized estimating equation indicated that perceived risk (β=0.5482; P<.001), perceived severity (β=0.0817; P=.007), and uncertainty stress (β=0.1776; P<.001) were positively associated with suicidal ideation. The number of new infections (β=0.0041; P=.49) was not significantly associated with suicidal ideation.
This study found that suicidal ideation gradually declined following the lifting of quarantine measures. Perceived risk, perceived severity, and uncertainty stress, rather than numbers of infected cases, were significantly associated with suicidal ideation. These findings highlight the importance of addressing individuals' perceptions with real-world context when developing effective strategies to manage COVID-19 and future infectious disease outbreaks.
为减缓新冠病毒病（COVID-19）的快速传播，许多国家采取了封锁和隔离措施。尽管这些措施对公共卫生有益，但其对自杀意念的影响尚未得到充分记录。
本研究旨在探讨在中国新冠疫情高峰期间，从隔离期到解除隔离期过渡阶段，COVID-19感染、感知信念、不确定性压力和自杀意念之间的关系。
采用前瞻性纵向观察设计。使用曼-肯德尔检验和 Cochr an - 阿米蒂奇检验评估6个时间点的变化趋势。使用广义估计方程分析自变量与自杀意念之间的关联。
共有221名（96.5%）参与者完成了全部6次观察。隔离期间自杀意念的患病率分别为16.7%（n = 37）、14.5%（n = 32）和14.5%（n = 32），而在解除隔离期间，分别为13.8%（n = 30）、10.9%（n = 24）和10.0%（n = 22）。观察到自杀意念有显著下降趋势。相比之下，感知风险、感知严重程度和新增感染病例数呈现显著上升趋势（z分数分别为9.56、7.13和3.69；P <.001、P <.001和P =.002）。然而，不确定性压力随时间保持稳定（z = 0.71；P =.48）。广义估计方程表明，感知风险（β = 0.5482；P <.001）、感知严重程度（β = 0.0817；P =.007）和不确定性压力（β = 0.1776；P <.001）与自杀意念呈正相关。新增感染病例数（β = 0.0041；P =.49）与自杀意念无显著关联。
本研究发现，解除隔离措施后自杀意念逐渐下降。与自杀意念显著相关的是感知风险、感知严重程度和不确定性压力，而非感染病例数。这些发现凸显了在制定有效策略应对COVID-19及未来传染病爆发时，结合实际情况关注个体认知的重要性。
