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[500例微创肝切除术——高手术量中心的经验、结果及技术进展]

[500 minimally invasive liver resections-Experiences, results and technical developments of a high-volume center].

作者信息

Abdelhadi Schaima, El-Ahmar Mohamad, Sandra-Petrescu Flavius, Reissfelder Christoph

机构信息

Chirurgische Klinik der Universitätsmedizin Mannheim, Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.

DKFZ-Hector Krebsinstitut an der Universitätsmedizin Mannheim, Mannheim, Deutschland.

出版信息

Chirurgie (Heidelb). 2025 Sep 6. doi: 10.1007/s00104-025-02373-1.

Abstract

BACKGROUND

Minimally invasive liver surgery has rapidly evolved in recent years. In addition to the laparoscopic liver resection (LLR), robot-assisted liver resection (RLR) is increasingly gaining in importance; however, although the robotic-assisted approach offers clinical benefits, particularly in complex procedures, it remains a matter of debate.

OBJECTIVE

The aim of this study was to present the development, perioperative outcomes, key challenges, and insights from over 500 minimally invasive liver resections performed at a specialized high-volume center. It focused on the comparison between LLR and RLR based on the IWATE difficulty score.

MATERIAL AND METHODS

A retrospective single-center analysis of 526 consecutive elective minimally invasive liver resections (2018-2024) was conducted. All cases were stratified using the IWATE score. The LLR and RLR were compared in terms of operative parameters, conversion rate and postoperative complications. Additionally, the annual procedural development was analyzed.

RESULTS

The RLR was established in 2021 and accounted for over 50% of all minimally invasive liver resections by 2024. Compared to LLR, RLR was associated with significantly reduced intraoperative blood loss as well as lower conversion and complication rates, particularly in technically demanding resections. Despite an increasing proportion of advanced/expert resections, the rate of major complications could be reduced over time.

CONCLUSION

Minimally invasive liver resections can be safely performed at high-volume centers. The robotic-assisted technique offers specific advantages especially in complex resections, with respect to complication rates, reduced conversion rates and decreased blood loss. A key success factor in the implementation of robotic liver surgery is the pre-existing expertise in laparoscopic techniques, which significantly shortened the learning curve. The use of standardized techniques such as the scissor hepatectomy may have contributed to the comparatively low rate of bile leaks observed in RLR.

摘要

背景

近年来,微创肝脏手术发展迅速。除了腹腔镜肝切除术(LLR)外,机器人辅助肝切除术(RLR)的重要性日益凸显;然而,尽管机器人辅助手术具有临床优势,尤其是在复杂手术中,但仍存在争议。

目的

本研究旨在介绍在一个专门的高容量中心进行的500多例微创肝切除手术的发展情况、围手术期结果、关键挑战和见解。重点基于岩手难度评分比较LLR和RLR。

材料与方法

对2018 - 2024年连续526例择期微创肝切除术进行回顾性单中心分析。所有病例均采用岩手评分进行分层。比较LLR和RLR的手术参数、转化率和术后并发症。此外,还分析了年度手术进展情况。

结果

RLR于2021年开展,到2024年占所有微创肝切除术的50%以上。与LLR相比,RLR的术中出血量显著减少,转化率和并发症发生率更低,尤其是在技术要求较高的切除术中。尽管高级/专家级切除术的比例不断增加,但随着时间的推移,主要并发症的发生率可以降低。

结论

高容量中心可以安全地进行微创肝切除术。机器人辅助技术尤其在复杂切除术中具有特定优势,在并发症发生率、降低转化率和减少出血量方面表现突出。机器人肝脏手术实施的一个关键成功因素是现有的腹腔镜技术专业知识,这显著缩短了学习曲线。使用标准化技术如剪刀式肝切除术可能有助于RLR中观察到的相对较低的胆漏发生率。

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