López-Labrador F Xavier, Blasco Adolfo, Villamayor Luis M, Gaume Gregoire, Ros-Lis José V
Virology Laboratory and BSL-3 Laboratory, Genomics and Health, FISABIO-Public Health, Valencia, Spain.
Department of Microbiology, University of Valencia Medical School and CIBERESP, Instituto de Salud Carlos III, Valencia, Spain.
Food Environ Virol. 2025 Sep 6;17(4):49. doi: 10.1007/s12560-025-09663-1.
The global emergence of SARS-CoV-2 has highlighted the urgent need for effective disinfection strategies to mitigate virus transmission. Electrolyzed water (EW), an eco-friendly and cost-effective biocidal agent, has garnered attention for its broad-spectrum antimicrobial activity. This study evaluates the virucidal, bactericidal, and fungicidal capacities of EW with diverse pH, with a focus on its effectiveness against SARS-CoV-2 and other pathogens. EW was generated under controlled conditions with adjustable pH (4.5 and 6.1) and free available chlorine (FAC) concentrations (300-1000 ppm). The biocidal activity was tested on surfaces and in solution following standardized protocols. Results demonstrated that oxidized EW at optimized concentrations achieved a ≥ 4 log reduction in bacterial populations and effectively inactivated enveloped and non-enveloped viruses, but this effect depends on FAC, pH, and contact time. Notably, EW reduced SARS-CoV-2 by > 4 log in solution and surfaces, in only 2 and 5 min, respectively. These findings highlight the potential of EW as a sustainable, multi-application disinfectant to combat emerging pathogens like SARS-CoV-2, ensuring public health safety.
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)在全球的出现凸显了采取有效消毒策略以减轻病毒传播的迫切需求。电解水(EW)是一种环保且经济高效的杀生物剂,因其广谱抗菌活性而受到关注。本研究评估了不同pH值的电解水的杀病毒、杀菌和杀真菌能力,重点关注其对SARS-CoV-2和其他病原体的有效性。在可控条件下生成电解水,其pH值(4.5和6.1)和游离有效氯(FAC)浓度(300 - 1000 ppm)可调。按照标准化方案在表面和溶液中测试其杀生物活性。结果表明,优化浓度的氧化电解水可使细菌数量减少≥4个对数,并有效灭活包膜病毒和非包膜病毒,但这种效果取决于游离有效氯、pH值和接触时间。值得注意的是,电解水在溶液和表面分别仅用2分钟和5分钟就能使SARS-CoV-2减少>4个对数。这些发现凸显了电解水作为一种可持续的、多用途消毒剂对抗SARS-CoV-2等新兴病原体、确保公共卫生安全的潜力。