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肿瘤人类学与非洲散居群体：二十年周年报告，国际乳腺癌亚型研究中心（ICSBCS）

Oncologic Anthropology and the African Diaspora: Twenty-Year Anniversary Report, International Center for the Study of Breast Cancer Subtypes (ICSBCS).

作者信息

Kyei Ishmael, Bea Vivian J, Gyan Kofi K, Adjei Ernest, Stonaker Brian, Bekele Mahteme, Abebe Engida, Davis Melissa, Boakye Andrew, Boateng Richard, Elemento Olivier, Aitpillah Frances, Alebachew Hanan, Jibril Aisha, Chen Yalei, Taiwo Evelyn, Bensenhaver Jessica, Walker Eleanor, Ali Haythem, Oppong Joseph, Ginter Paula, Nalwoga Hawa, Kalungi Sam, Ebughe Godwin, Ezeome Emmanuel R, Jackson Karen, Bonsu Ernest Osei, Momoh Adeyiza, Martini Rachel, Demaria Sandra, Yates Clayton, Balogun Onyinye D, Louie Christopher, Manohar Jyothi, Bediako Yaw, Boaitey Gloria Agyekum, Fondjo Linda Ahenkorah, Iloanusi Nneka, Okoye Ifeoma, Adinku Michael, Ankomah Kwasi, Dally Charles, Rockefeller Emily, Susick Laura, Obong-Ekanem Ima, Greenspun Benjamin C, Daba Shimelis Abegaz, Schwartz Theresa, Robine Nicolas, Chen Shuibing, Carrot-Zhang Jian, Amazu Setor, Jiagge Evelyn, Acheamfour Osei Kareem, Patino Stevens, Malik Manmeet, Ju Tammy, Siegel Beth, Martin Iman Khalifa, Mills Cassandra, Phillip Jocelyn, Kalu Chima Onwuka, Joseph Christine, Peters Favour, Stromain Amanda, Olusina Bankole, Nwokoro Onyekachi, Lasebikan Nwamaka, Udosen Joseph, Nwagbara Victor, Carpten John, Fisseha Senait, Johnson Timothy, Awuah Baffour, Newman Lisa A

机构信息

Department of Surgery, Komfo Anoyke Teaching Hospital, Kumasi, Ghana.

Department of Surgery, Weill Cornell Medicine, New York, NY, USA.

出版信息

Ann Surg Oncol. 2025 Sep 6. doi: 10.1245/s10434-025-17807-7.

DOI:10.1245/s10434-025-17807-7

PMID:40914775

Abstract

The International Center for the Study of Breast Cancer Subtypes (ICSBCS) has played a vital role in defining and overcoming many inequities that exist in breast cancer treatment and outcome on a global basis through capacity-building programs that improve the management of breast cancer patients across the African diaspora. ICSBCS activities also fill critical gaps in disparities research related to the genetics of ancestry. Over the past 20 years, ICSBCS teams have spearheaded landmark studies documenting the relevance of genetic African ancestry to breast cancer risk, while also improving the quality of care delivered to patients in diverse communities. Herein, the achievements and future goals of this international, multi-institutional breast cancer research and outreach program are summarized.

摘要

国际乳腺癌亚型研究中心（ICSBCS）通过能力建设项目在界定和克服全球乳腺癌治疗及预后方面存在的诸多不平等现象中发挥了至关重要的作用，这些项目改善了散居在非洲各地的乳腺癌患者的管理。ICSBCS的活动还填补了与祖先遗传学相关的差异研究中的关键空白。在过去20年里，ICSBCS团队率先开展了具有里程碑意义的研究，记录了非洲遗传血统与乳腺癌风险的相关性，同时还提高了为不同社区患者提供的护理质量。在此总结该国际多机构乳腺癌研究及推广项目的成就和未来目标。