Bracken M B, Bryce-Buchanan C, Stilten R, Holford T
Ann Hum Biol. 1985 Nov-Dec;12(6):525-31. doi: 10.1080/03014468500008101.
Among women who habitually miscarried (two or more miscarriages) we observed a modest association for increased risk of miscarriage of first pregnancies in those with younger (especially less than or equal to 11 years) and older (greater than or equal to 16 years) menarcheal age (quadratic G2 = 3.49, P = 0.062). No associations of menarcheal age with first pregnancy miscarriage were observed when analysed by age at first pregnancy, or with pregnancy number among women with only one miscarriage. Unusually early or late menarcheal age appears to increase the risk of miscarriage of the first pregnancy but only among women who will go on to habitually miscarry.
在习惯性流产（两次或更多次流产）的女性中，我们观察到月经初潮年龄较小（尤其是小于或等于11岁）和较大（大于或等于16岁）的女性首次怀孕流产风险增加之间存在适度关联（二次G2 = 3.49，P = 0.062）。按首次怀孕年龄分析时，未观察到月经初潮年龄与首次怀孕流产之间的关联，在仅有一次流产的女性中，也未观察到月经初潮年龄与怀孕次数之间的关联。异常早或晚的月经初潮年龄似乎会增加首次怀孕流产的风险，但仅在那些会继续习惯性流产的女性中如此。
