Özyaprak Buket, Kılıçarslan Nermin, Apaydın Yılmaz, Balk Şule, Karasu Derya, İskender Abdulkadir, Gamlı Mehmet, Güler Gürcan, Uzsezer Güler Begüm, Ceylan İlkay
Department of Anesthesiology and Reanimation, Bursa Yüksek Ihtisas Training and Research Hospital, University of Health Science, Bursa, Turkey.
Department of Anesthesiology and Reanimation, Basaksehir Cam and Sakura City Hospital, İstanbul, Turkey.
Med Sci Monit. 2025 Sep 8;31:e949693. doi: 10.12659/MSM.949693.
BACKGROUND Pregnancy-related anatomical and physiological changes, such as mucosal edema and increased oxygen demand, heighten risk of difficult airway, especially under general anesthesia. This study compared effects of spinal and general anesthesia on postoperative airway assessment tests in cesarean deliveries. We hypothesized upper airway changes can occur depending on anesthesia technique. MATERIAL AND METHODS This prospective observational study included 100 pregnant women undergoing elective cesarean delivery. Patients were divided into 2 groups according to anesthesia type: spinal (n=64) and general (n=36). Five basic airway assessment tests (modified Mallampati score, thyromental distance, sternomental distance, neck circumference, and upper lip bite test) were performed preoperatively and 1, 6, and 24 h after surgery (T1-T4). RESULTS No significant changes were observed over time in the spinal group (all P>0.05), with Mallampati scores remaining stable from T1 to T4 (mean T1: 1.7±0.6; T4: 1.8±0.5). In contrast, general anesthesia group showed a significant increase in Mallampati scores at T2 (T1: 1.7±0.6 vs T2: 2.4±0.7, P<0.001). Postoperative nausea and vomiting were more frequent in the general anesthesia group (27.8% vs 10.9%, P=0.016). In hemodynamic evaluation, systolic and diastolic blood pressure values were significantly higher at the 2nd and 5th minutes in the general anesthesia group (2nd min SBP: 128.4±20.6 mmHg vs 114.5±17.4 mmHg; 5th min SBP: 121.4±15.6 mmHg vs 107.1±14.7 mmHg; both P<0.001). CONCLUSIONS The significant increase in Mallampati scores after general anesthesia highlights the potential for upper airway edema due to intubation. Anticipating this risk is important for airway safety in the early postpartum period.
背景 与妊娠相关的解剖和生理变化,如黏膜水肿和氧需求增加,会增加气道困难的风险,尤其是在全身麻醉下。本研究比较了剖宫产中脊髓麻醉和全身麻醉对术后气道评估测试的影响。我们假设上气道变化可能因麻醉技术而异。
材料与方法 这项前瞻性观察性研究纳入了100例行择期剖宫产的孕妇。根据麻醉类型将患者分为两组:脊髓麻醉组(n = 64)和全身麻醉组(n = 36)。术前以及术后1、6和24小时(T1 - T4)进行五项基本气道评估测试(改良Mallampati评分、颏甲距离、胸骨颏距离、颈围和上唇咬合试验)。
结果 脊髓麻醉组随时间未观察到显著变化(所有P>0.05),从T1到T4,Mallampati评分保持稳定(平均T1:1.7±0.6;T4:1.8±0.5)。相比之下,全身麻醉组在T2时Mallampati评分显著增加(T1:1.7±0.6 vs T2:2.4±0.7,P<0.001)。全身麻醉组术后恶心和呕吐更为频繁(27.8% vs 10.9%,P = 0.016)。在血流动力学评估中,全身麻醉组在第2分钟和第5分钟时收缩压和舒张压值显著更高(第2分钟收缩压:128.4±20.6 mmHg vs 114.5±17.4 mmHg;第5分钟收缩压:121.4±15.6 mmHg vs 107.1±14.7 mmHg;两者P<0.001)。
结论 全身麻醉后Mallampati评分显著增加突出了插管导致上气道水肿的可能性。认识到这种风险对产后早期气道安全很重要。