García Oliveros Irma, Meabe Iturbe Nerea, Marín Ojea Juan Ignacio, Lancho Poblador Carolina, Fuentes-Claramonte Paola, Quemada Ubis José Ignacio
Servicio de Daño Cerebral, Hospital Aita Menni, 48010 Bilbao, Bizkaia, Spain.
Servicio de Daño Cerebral, Hospital Aita Menni, 20509 Mondragón, Gipuzkoa, Spain.
Rev Neurol. 2025 Aug 29;80(7):46141. doi: 10.31083/RN46141.
To evaluate the impact of intensive gait training on gross motor function using the pediatric exoskeleton ATLAS 2030, as well as to determine the post-intervention maintenance of effects in children with cerebral palsy (CP).
A non-randomized controlled prospective study. Thirteen children with CP participated. A program of four weekly sessions lasting 65 minutes each was implemented over six weeks. Gross motor function was assessed using the 88 items Gross Motor Function Measure (GMFM-88); physical exercise endurance was measured with the Six-Minute Walk Test (6MWT) using the device; the number of steps walked in each session and mode of use was recorded to evaluate adaptation to the activity. Three evaluations were conducted: before treatment, at the end of treatment (6 weeks), and a follow-up evaluation at 12 weeks.
The total GMFM-88 score showed significant changes at the end of the intervention (p < 0.001), which persisted at follow-up (p < 0.001). The number of steps in automatic and active modes increased significantly after the intervention (p < 0.001) and were maintained at follow-up (p = 0.001). Lastly, the 6MWT improved significantly after the intervention, with a reduction observed at follow-up (p < 0.001).
Six weeks of intensive training with ATLAS 2030 positively impacts the gross motor function of children with CP, with benefits increasing six weeks after treatment completion. Physical endurance and adaptation to the activity improve with continued use. These results support the potential of ATLAS 2030 as an intensive therapeutic strategy for this population.
No: NCT07066956. https://clinicaltrials.gov/search?cond=NCT07066956.
评估使用儿科外骨骼ATLAS 2030进行强化步态训练对粗大运动功能的影响，并确定脑瘫（CP）患儿干预效果的后期维持情况。
一项非随机对照前瞻性研究。13名CP患儿参与。在六周内实施了一个为期四周的计划，每周进行一次，每次持续65分钟。使用88项粗大运动功能测量量表（GMFM - 88）评估粗大运动功能；使用该设备通过六分钟步行试验（6MWT）测量身体运动耐力；记录每次训练中行走的步数和使用模式，以评估对该活动的适应性。进行了三次评估：治疗前、治疗结束时（6周）以及12周的随访评估。
干预结束时GMFM - 88总分显示出显著变化（p < 0.001），随访时仍持续存在（p < 0.001）。干预后自动和主动模式下的步数显著增加（p < 0.001），随访时保持不变（p = 0.001）。最后，干预后6MWT显著改善，随访时有所下降（p < 0.001）。
使用ATLAS 2030进行六周强化训练对CP患儿的粗大运动功能有积极影响，治疗完成六周后益处增加。持续使用可改善身体耐力和对活动的适应性。这些结果支持ATLAS 2030作为该人群强化治疗策略的潜力。
编号：NCT07066956。https://clinicaltrials.gov/search?cond=NCT07066956 。
