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脊椎椎间盘炎:一例病例报告及文献综述

Spondylodiscitis: A Case Report and Review of the Literature.

作者信息

S Sivalingam Suranthaniy, Prendki Virginie, Garin Nicolas

机构信息

Division of Internal Medicine, Riviera Chablais Hospital, Rennaz, Switzerland.

Division of Internal Medicine for the Aged, Geneva University Hospitals, Geneva, Switzerland.

出版信息

Case Rep Infect Dis. 2025 Aug 28;2025:1569042. doi: 10.1155/crdi/1569042. eCollection 2025.

DOI:10.1155/crdi/1569042
PMID:40917078
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12411054/
Abstract

, a rare human pathogen, mainly causes urinary tract infection, endocarditis, and bacteremia. However, it is rarely the cause of other types of infection such as spondylodiscitis. Invasive infection chiefly occurs in older men with underlying urinary tract disorders. The real incidence may be underestimated, as grow in a CO2-containing atmosphere, and urine cultures are usually not incubated in this environment. There have been eight case reports of spondylodiscitis due to We report a 9 case occurring in an 80-year-old Caucasian man with lower back pain. The patient had predisposing conditions (diabetes and a history of urological surgery). Spinal MRI showed signs of spondylodiscitis. Two computed tomography-guided biopsies targeting the intervertebral disc and psoas muscle were not diagnostic. One of 10 blood culture bottles grew . After worsening of an L2 fracture, and unsuccessful percutaneous sampling procedures, the patient underwent surgical stabilization of T12 to L4 with multiple biopsies. Biopsy cultures grew . Amoxicillin was administered intravenously for 14 days, followed by oral levofloxacin for 3 months. should be considered in spondylodiscitis with negative cultures, particularly in older men with diabetes and urological conditions.

摘要

[病原体名称],一种罕见的人类病原体,主要引起尿路感染、心内膜炎和菌血症。然而,它很少是其他类型感染(如脊椎椎间盘炎)的病因。侵袭性感染主要发生在患有潜在泌尿系统疾病的老年男性中。实际发病率可能被低估,因为[病原体名称]在含二氧化碳的环境中生长,而尿培养通常不在这种环境中进行孵育。已有8例因[病原体名称]导致脊椎椎间盘炎的病例报告。我们报告1例发生在一名80岁白种男性身上的病例,该患者有下背部疼痛。患者有易感因素(糖尿病和泌尿外科手术史)。脊柱磁共振成像显示有脊椎椎间盘炎的迹象。针对椎间盘和腰大肌进行的两次计算机断层扫描引导下活检未得出诊断结果。10个血培养瓶中有1个培养出[病原体名称]。在L2骨折病情恶化且经皮采样程序未成功后,患者接受了T12至L4的手术固定并进行了多次活检。活检培养物培养出[病原体名称]。静脉注射阿莫西林14天,随后口服左氧氟沙星3个月。对于培养结果为阴性的脊椎椎间盘炎,尤其是患有糖尿病和泌尿系统疾病的老年男性,应考虑[病原体名称]感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8082/12411054/05c2098f57d3/CRIID2025-1569042.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8082/12411054/4e9f5bb92854/CRIID2025-1569042.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8082/12411054/0a8edba38c06/CRIID2025-1569042.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8082/12411054/ec6236104478/CRIID2025-1569042.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8082/12411054/05c2098f57d3/CRIID2025-1569042.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8082/12411054/4e9f5bb92854/CRIID2025-1569042.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8082/12411054/0a8edba38c06/CRIID2025-1569042.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8082/12411054/ec6236104478/CRIID2025-1569042.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8082/12411054/05c2098f57d3/CRIID2025-1569042.004.jpg

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本文引用的文献

1
Oral Therapy for Bacteremia and Thoracic Spondylodiscitis of Presumed Urinary Origin.针对推测源于泌尿系统的菌血症和胸椎椎间盘炎的口服治疗
Fed Pract. 2022 Dec;39(12):482-485. doi: 10.12788/fp.0340. Epub 2022 Dec 16.
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Aerococcus urinae, a rare cause of aortic root abscess: a case report.解脲脲原体致主动脉根部脓肿罕见病因:1 例报告。
J Med Case Rep. 2022 Nov 17;16(1):438. doi: 10.1186/s13256-022-03564-8.
3
Spondylodiscitis in adults: diagnosis and management.成人脊椎炎:诊断与治疗。
Br J Hosp Med (Lond). 2022 Oct 2;83(10):1-9. doi: 10.12968/hmed.2021.0448. Epub 2022 Oct 30.
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Clinical and microbiological characterization of Aerococcus urinae bacteraemias at Helsinki metropolitan area, Finland.芬兰赫尔辛基大都市区解脲尿球菌菌血症的临床和微生物学特征。
Eur J Clin Microbiol Infect Dis. 2022 May;41(5):751-760. doi: 10.1007/s10096-022-04415-6. Epub 2022 Mar 8.
5
Spondylodiscitis: An Increasingly Described Localization.脊椎椎间盘炎:一种描述日益增多的发病部位。
EJIFCC. 2020 Jun 2;31(2):169-173. eCollection 2020 Jun.
6
Multidisciplinary management of pyogenic spondylodiscitis: epidemiological and clinical features, prognostic factors and long-term outcomes in 207 patients.化脓性脊椎椎间盘炎的多学科管理:207例患者的流行病学和临床特征、预后因素及长期结局
Eur Spine J. 2018 Jun;27(Suppl 2):229-236. doi: 10.1007/s00586-018-5598-9. Epub 2018 Apr 17.
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Aerococcus urinae: an underestimated cause of spine infection? Case report and review of the literature.尿液气球菌:脊柱感染的一个被低估的病因?病例报告及文献综述
Acta Clin Belg. 2018 Dec;73(6):444-447. doi: 10.1080/17843286.2018.1443003. Epub 2018 Mar 2.
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Spondylodiscitis due to Aerococcus urinae and literature review.尿肠球菌致椎间盘炎并文献复习。
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Yield of Image-Guided Needle Biopsy for Infectious Discitis: A Systematic Review and Meta-Analysis.影像学引导下的感染性椎间盘炎的活检的产量:系统评价和荟萃分析。
AJNR Am J Neuroradiol. 2017 Oct;38(10):2021-2027. doi: 10.3174/ajnr.A5337. Epub 2017 Sep 7.
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Spondylodiscitis due to Aerococcus urinae infection in an elderly immunocompetent patient.一名免疫功能正常的老年患者因尿液气球菌感染导致脊椎椎间盘炎。
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