Department of Diagnostic & Clinical Pathology, University of Saskatchewan, Saskatoon, S7N 0W8, Canada.
Department of Clinical Microbiology, Saskatchewan Health Authority, Saskatoon, S7N 0W8, Canada.
Future Microbiol. 2024;19(15):1321-1332. doi: 10.1080/17460913.2024.2383503. Epub 2024 Aug 7.
and are emerging pathogens linked with urinary tract infections. We present a case series of and isolates characterizing the spectrum of clinical presentation, microbiological characteristics and antimicrobial sensitivities. Retrospective chart review was performed on patients who grew positive cultures for and identified on MALDI-TOF in Saskatchewan from January to June 2023. Demographic and clinical variables, antimicrobial susceptibility and prescription were documented. This cohort (n = 115) had a median age 82 years. and infections spanned from urinary tract infection (n = 96) to urosepsis (n = 6). These infections were predominantly monomicrobial (73.9%) and were susceptible to ceftriaxone, penicillin G and vancomycin. Antimicrobials were seldom prescribed within the urinary tract infection cohort (31.2%). Untreated and infections can precipitate into urosepsis. The reported antimicrobial susceptibility for these isolates should be utilized to provide appropriate antimicrobial coverage.
和 是与尿路感染相关的新兴病原体。我们报告了一系列 和 分离株的病例,这些分离株的特征在于临床表现、微生物学特征和抗菌敏感性的范围。对 2023 年 1 月至 6 月在萨斯喀彻温省通过 MALDI-TOF 鉴定为 和 的阳性培养物患者进行了回顾性图表审查。记录了人口统计学和临床变量、抗菌药物敏感性和处方。该队列(n=115)的中位年龄为 82 岁。和 感染从尿路感染(n=96)到尿脓毒症(n=6)不等。这些感染主要是单微生物感染(73.9%),对头孢曲松、青霉素 G 和万古霉素敏感。在尿路感染组中很少开抗菌药物(31.2%)。未治疗的 和 感染可能会引发尿脓毒症。应利用这些分离株的报告抗菌药物敏感性来提供适当的抗菌药物覆盖。