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复发性播散性腹膜平滑肌瘤病:一例报告

Recurrent leiomyomatosis peritonealis disseminate: a case report.

作者信息

Mensah Yaw B, Buadi Lawrence, Abrahams Afua, Appau Andrea A Y, Mensah Kwadwo

机构信息

Department of Radiology, University of Ghana Medical School, Korle Bu, Accra.

Department of Obstetrics and Gynaecology, Trauma and Specialist Hospital, Winneba, Ghana.

出版信息

Ghana Med J. 2021 Jun;55(2):160-164. doi: 10.4314/gmj.v55i2.11.

Abstract

UNLABELLED

Leiomyomatosis peritonealis disseminata (LPD), a rare and unusual condition affecting mainly women of reproductive age, causes peritoneal and subperitoneal nodules formed by smooth muscle. Very few cases have been diagnosed since the disease was first described. We present a 42year old female who was managed for infertility and uterine myomata at a Municipal hospital in Ghana. Following a pelvic ultrasound diagnosis of multiple uterine myomata the patient was booked for myomectomy. At surgery to remove her myomata, the patient was found to have several peritoneal nodules some of which were attached to peritoneum, omentum and the surface of bowel loops in addition to a uterine myoma. The disease has since recurred twice after two laparotomies. The diagnosis was made by histopathology of ultrasound-guided biopsy of the nodules, and she has since been on GnRH analogue treatment. LPD simulates peritoneal carcinomatosis; thus, a good history, clinical evaluation, radiological imaging, and histopathologic analysis must be accurately diagnosed. Surgeons' and Radiologists' knowledge of the condition is fundamental to ensuring correct diagnosis and appropriate treatment and to minimising the probability of malignant transformation.

FUNDING

None declared.

摘要

未标注

播散性腹膜平滑肌瘤病(LPD)是一种罕见且特殊的疾病,主要影响育龄女性,会导致由平滑肌形成的腹膜和腹膜下结节。自该疾病首次被描述以来,诊断出的病例极少。我们报告一名42岁女性,她在加纳一家市立医院因不孕症和子宫肌瘤接受治疗。经盆腔超声诊断为多发性子宫肌瘤后,该患者预定接受肌瘤切除术。在切除肌瘤的手术中,除了子宫肌瘤外,还发现患者有多个腹膜结节,其中一些附着于腹膜、大网膜和肠袢表面。自两次剖腹手术后,该病已复发两次。通过对结节进行超声引导下活检的组织病理学检查做出诊断,此后她一直在接受促性腺激素释放激素类似物治疗。LPD类似腹膜癌;因此,必须通过详细病史、临床评估、影像学检查和组织病理学分析才能准确诊断。外科医生和放射科医生对该疾病的了解对于确保正确诊断和适当治疗以及将恶性转化的可能性降至最低至关重要。

资金来源

未声明。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1d6/12410026/26f040a382a0/GMJ5502-0160Fig1.jpg

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