• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

-（3-氯-4-羟基苯基）乙酰胺

-(3-Chloro-4-hy-droxy-phen-yl)acetamide.

作者信息

Uppu Rao M, Fronczek Frank R

机构信息

Department of Environmental Toxicology Southern University and A&M College Baton Rouge Louisiana 70813 USA.

Department of Chemistry Louisiana State University,Baton Rouge Louisiana 70803 USA.

出版信息

IUCrdata. 2025 Aug 5;10(Pt 8):x250695. doi: 10.1107/S2414314625006959. eCollection 2025 Aug.

DOI:10.1107/S2414314625006959
PMID:40917535
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12412683/
Abstract

In the title compound, CHClNO, the acetamide substituent is twisted out of the phenyl plane, forming a dihedral angle of 58.61 (7)°. In the extended structure, each mol-ecule donates two hydrogen bonds [N-H⋯O(carbon-yl) and O-H⋯O(carbon-yl)] and thus also accepts two such hydrogen bonds. The chlorine atom is not involved in the hydrogen bonding.

摘要

在标题化合物CHClNO中，乙酰胺取代基扭转出苯平面，形成58.61 (7)°的二面角。在扩展结构中，每个分子提供两个氢键[N-H⋯O（羰基）和O-H⋯O（羰基）]，因此也接受两个这样的氢键。氯原子不参与氢键形成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e88/12412683/192fef0fca9c/x-10-x250695-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e88/12412683/c85e6fa58c39/x-10-x250695-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e88/12412683/68aa17ebe141/x-10-x250695-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e88/12412683/192fef0fca9c/x-10-x250695-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e88/12412683/c85e6fa58c39/x-10-x250695-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e88/12412683/68aa17ebe141/x-10-x250695-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e88/12412683/192fef0fca9c/x-10-x250695-fig3.jpg

相似文献

1
-(3-Chloro-4-hy-droxy-phen-yl)acetamide.-（3-氯-4-羟基苯基）乙酰胺
IUCrdata. 2025 Aug 5;10(Pt 8):x250695. doi: 10.1107/S2414314625006959. eCollection 2025 Aug.
2
2-Chloro--(4-hy-droxy-phen-yl)acetamide.2-氯-（4-羟基苯基）乙酰胺。 需注意，原文中“2-Chloro--(4-hy-droxy-phen-yl)acetamide”存在多余的连字符，正确的应该是“2-Chloro-(4-hydroxy-phenyl)acetamide” 。
IUCrdata. 2024 Oct 24;9(Pt 10):x241015. doi: 10.1107/S2414314624010150. eCollection 2024 Oct.
3
Synthesis and structure of ()--(4-meth-oxy-phen-yl)-2-[4-(3-oxo-3-phenyl-prop-1-en-1-yl)phen-oxy]acetamide.（）-（4-甲氧基苯基）-2-[4-（3-氧代-3-苯基丙-1-烯-1-基）苯氧基]乙酰胺的合成与结构
Acta Crystallogr E Crystallogr Commun. 2021 Jan 29;77(Pt 2):184-189. doi: 10.1107/S2056989021000864. eCollection 2021 Feb 1.
4
2-[(E)-(3-Carb-oxy-4-hy-droxy-phen-yl)iminiometh-yl]-4-chloro-phenolate.2-[(E)-(3-羧基-4-羟基苯基)亚氨基甲基]-4-氯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2010 Aug 28;66(Pt 9):o2466. doi: 10.1107/S1600536810033362.
5
-(4-Meth-oxy-2-methyl-5-nitro-phen-yl)acetamide.-（4-甲氧基-2-甲基-5-硝基苯基）乙酰胺
IUCrdata. 2025 Jun 3;10(Pt 6):x250470. doi: 10.1107/S2414314625004705. eCollection 2025 Jun.
6
Crystal structure of N-[3-(2-chloro-benzo-yl)-5-ethyl-thio-phen-2-yl]-2-[(E)-(2-hy-droxy-benzyl-idene)amino]-acetamide.N-[3-(2-氯苯甲酰基)-5-乙硫基-2-苯基]-2-[(E)-(2-羟基亚苄基)氨基]乙酰胺的晶体结构
Acta Crystallogr Sect E Struct Rep Online. 2014 Aug 16;70(Pt 9):o1011-2. doi: 10.1107/S1600536814018224. eCollection 2014 Sep 1.
7
N-Benzyl-2-(3-chloro-4-hy-droxy-phen-yl)acetamide.N-苄基-2-(3-氯-4-羟基苯基)乙酰胺
Acta Crystallogr Sect E Struct Rep Online. 2010 Sep 8;66(Pt 10):o2521. doi: 10.1107/S1600536810035397.
8
Crystal structure of (2E)-3-(3-eth-oxy-4-hy-droxy-phen-yl)-1-(4-hy-droxy-phen-yl)prop-2-en-1-one.（2E）-3-（3-乙氧基-4-羟基苯基）-1-（4-羟基苯基）丙-2-烯-1-酮的晶体结构
Acta Crystallogr Sect E Struct Rep Online. 2014 Oct 29;70(Pt 11):o1202-3. doi: 10.1107/S1600536814023368. eCollection 2014 Nov 1.
9
4-Chloro-curcumin.4-氯姜黄素。
IUCrdata. 2025 Jan 3;10(Pt 1):x241243. doi: 10.1107/S2414314624012434. eCollection 2025 Jan.
10
Bis(4-hy-droxy-phen-yl) 1,4-phenyl-enebiscarbamate.双（4-羟基苯基）1,4-亚苯基双氨基甲酸酯
IUCrdata. 2022 Sep 27;7(Pt 9):x220919. doi: 10.1107/S2414314622009191. eCollection 2022 Sep.

本文引用的文献

1
Occurrence of 97 Pharmaceuticals in Wastewater and Receiving Waters: Analytical Validation and Treatment Influence.废水中及受纳水体中97种药物的存在情况：分析验证及处理影响
J Xenobiot. 2025 May 23;15(3):78. doi: 10.3390/jox15030078.
2
,'-[Oxybis(benzene-4,1-di-yl)]diacetamide.,-[氧代双(苯-4,1-二亚基)]二乙酰胺。
IUCrdata. 2025 May 2;10(Pt 5):x250384. doi: 10.1107/S2414314625003840. eCollection 2025 May.
3
Formation of Larger Molecular Weight Disinfection Byproducts from Acetaminophen in Chlorine Disinfection.在氯消毒中，从对乙酰氨基酚形成更大分子量的消毒副产物。
Environ Sci Technol. 2022 Dec 6;56(23):16929-16939. doi: 10.1021/acs.est.2c06394. Epub 2022 Nov 21.
4
A review on the degradation of acetaminophen by advanced oxidation process: pathway, by-products, biotoxicity, and density functional theory calculation.高级氧化法降解对乙酰氨基酚的综述：途径、副产物、生物毒性及密度泛函理论计算
RSC Adv. 2022 Jun 22;12(29):18373-18396. doi: 10.1039/d2ra02469a.
5
Degradation of Acetaminophen via UVA-induced advanced oxidation processes (AOPs). Involvement of different radical species: HO, SO and HO/O.通过 UVA 诱导的高级氧化工艺（AOPs）降解对乙酰氨基酚。涉及不同的自由基种类：HO、SO 和 HO/O。
Chemosphere. 2020 Nov;258:127268. doi: 10.1016/j.chemosphere.2020.127268. Epub 2020 Jun 12.
6
: from visualization to analysis, design and prediction.从可视化到分析、设计与预测。
J Appl Crystallogr. 2020 Feb 1;53(Pt 1):226-235. doi: 10.1107/S1600576719014092.
7
Acetaminophen micropollutant: Historical and current occurrences, toxicity, removal strategies and transformation pathways in different environments.对乙酰氨基酚微污染物：在不同环境中的历史和当前出现情况、毒性、去除策略和转化途径。
Chemosphere. 2019 Dec;236:124391. doi: 10.1016/j.chemosphere.2019.124391. Epub 2019 Jul 22.
8
Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update.对乙酰氨基酚诱导的肝毒性：全面更新。
J Clin Transl Hepatol. 2016 Jun 28;4(2):131-42. doi: 10.14218/JCTH.2015.00052. Epub 2016 Jun 15.
9
Transformation of acetaminophen during water chlorination treatment: kinetics and transformation products identification.对乙酰氨基酚在水氯化处理过程中的转化：动力学及转化产物鉴定
Environ Sci Pollut Res Int. 2016 Jun;23(12):12303-11. doi: 10.1007/s11356-016-6341-x. Epub 2016 Mar 17.
10
Comparison of silver and molybdenum microfocus X-ray sources for single-crystal structure determination.用于单晶结构测定的银和钼微焦点X射线源的比较。
J Appl Crystallogr. 2015 Jan 30;48(Pt 1):3-10. doi: 10.1107/S1600576714022985. eCollection 2015 Feb 1.