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孕期身体活动水平与早产及婴儿肥胖的关联:来自印度MAASTHI队列的纵向分析

Association of physical activity level during pregnancy with preterm birth and infant adiposity: longitudinal analysis from the MAASTHI cohort, India.

作者信息

Ana Yamuna, van den Brand Floor A, van Schayck Onno C P, Babu Giridhara R

机构信息

Department of Family Medicine, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, Limburg The Netherlands.

Indian Institute of Public Health-Bengaluru, Public Health Foundation of India (PHFI), Bengaluru, India.

出版信息

Sport Sci Health. 2025;21(3):1929-1940. doi: 10.1007/s11332-025-01409-7. Epub 2025 May 8.

DOI:10.1007/s11332-025-01409-7
PMID:40918267
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12408731/
Abstract

BACKGROUND

Physical activity during pregnancy is thought to influence birth outcomes, but its association with it is not fully understood. We aimed to examine the association of sedentary behavior during pregnancy with preterm birth and infant adiposity measured at birth, 14 weeks, and one year of age.

METHODS

In this cohort study, physical activity during pregnancy was assessed using the physical activity questionnaire. Gestational age at birth was determined soon after delivery and the infants were followed up until one year of age. Infant anthropometric measurements such as weight, length, crown-rump length, mid-upper arm circumference, waist and hip circumference, and skinfold thickness were assessed at each follow-up visit. Multivariable linear and logistic regression models were used to assess the association of sedentary behavior during pregnancy with preterm birth and infant adiposity, after adjusting for confounders.

RESULTS

Among the 1315 pregnant women who participated in the study, 7.1% had sedentary behavior. Sedentary behavior during pregnancy was significantly associated with a higher incidence of preterm birth (OR = 1.43,  = 0.041). Sedentary behavior during pregnancy showed a significant association with adiposity in children as measured through hip circumference (OR = 2.53,  = 0.007) at the 14-week follow-up and the sum of skinfold thickness (OR = 1.53,  = 0.024) at one-year follow-up.

CONCLUSION

This study highlights a significant association between sedentary behavior during pregnancy and preterm birth, markers of adiposity in children from birth to one year of age. These findings underscore the importance of maintaining moderate physical activity during pregnancy.

摘要

背景

孕期身体活动被认为会影响分娩结局,但其与之的关联尚未完全明确。我们旨在研究孕期久坐行为与早产以及出生时、14周和1岁时测量的婴儿肥胖之间的关联。

方法

在这项队列研究中,使用身体活动问卷评估孕期身体活动情况。分娩后不久确定出生时的孕周,并对婴儿进行随访直至1岁。每次随访时评估婴儿的人体测量指标,如体重、身长、顶臀长、上臂中部周长、腰围和臀围以及皮褶厚度。在调整混杂因素后,使用多变量线性和逻辑回归模型评估孕期久坐行为与早产和婴儿肥胖之间的关联。

结果

在参与研究的1315名孕妇中,7.1%有久坐行为。孕期久坐行为与早产发生率较高显著相关(OR = 1.43,P = 0.041)。孕期久坐行为在14周随访时与通过臀围测量的儿童肥胖显著相关(OR = 2.53,P = 0.007),在1年随访时与皮褶厚度总和显著相关(OR = 1.53,P = 0.024)。

结论

本研究强调了孕期久坐行为与早产以及出生至1岁儿童肥胖指标之间的显著关联。这些发现强调了孕期保持适度身体活动的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1ab/12408731/d035bf91ffc5/11332_2025_1409_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1ab/12408731/d035bf91ffc5/11332_2025_1409_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1ab/12408731/d035bf91ffc5/11332_2025_1409_Fig1_HTML.jpg

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