Jiangsu Vocational Institute of Commerce, Nanjing, 211168, China.
Office of Clinical Research Center, Children's Hospital of Nanjing Medical University, Nanjing, 210008, China.
BMC Public Health. 2022 Sep 12;22(1):1733. doi: 10.1186/s12889-022-14074-z.
Effect of physical exercise on pregnant women currently has become a hot topic in prenatal health care. In this study, A meta-analysis was conducted on account of Randomized Controlled Trial (RCT). It focused on evaluating the effect of physical exercise intervention on blood pressure so that could provide certain evidence for health care during pregnancy.
Results of relevant studies were retrieved from PubMed, Embase, Web of Science and the Cochrane Library, and all of these included studies were evaluated according to the Cochrane collaboration's tool for assessing the risk of bias. Stata 15.1 was used for meta-analysis, and mean difference (MD) was used as statistic for pooled analysis. The effect values were combined by conventional meta-analysis and Bayesian meta-analysis respectively, and the consistency of pooled results was considered as well.
A total of 18 RCT studies were included in the quantitative analysis. The conventional meta-analysis showed differences in blood pressure between intervention group and control group (P < 0.05). Systolic and diastolic blood pressures of intervention group were 3.19 mmHg (95% CI: -5.13, -1.25) and 2.14 mmHg (95% CI: -4.26, -0.03) lower than that of control group, respectively. Bayesian meta-analysis showed that both systolic and diastolic pressure among intervention group decreased by 3.34 mmHg (95% CrI: -5.15, -1.56) and 2.14 mmHg (95% CrI: -3.79, - 0.50), respectively. Subgroup analysis supported that as long as healthy pregnant women participated in exercises, their blood pressure could be slightly regulated, while hypertension susceptible pregnant women significantly lowered blood pressure.
Exercise intervention during pregnancy is beneficial to lower or normalize blood pressure, and this research provides clues for follow-up studies.
运动对孕妇的影响目前已成为产前保健的热门话题。本研究通过对随机对照试验（RCT）进行荟萃分析，旨在评估运动干预对血压的影响，为孕期保健提供一定依据。
检索 PubMed、Embase、Web of Science 和 Cochrane Library 中相关研究的结果，根据 Cochrane 协作对偏倚风险的评估工具对纳入的研究进行评价。采用 Stata 15.1 进行荟萃分析，用均数差（MD）进行汇总分析。分别采用传统荟萃分析和贝叶斯荟萃分析对效应值进行合并，并考虑汇总结果的一致性。
共纳入 18 项 RCT 研究进行定量分析。传统荟萃分析显示干预组与对照组之间的血压存在差异（P<0.05）。干预组收缩压和舒张压分别低对照组 3.19mmHg（95%CI：-5.13，-1.25）和 2.14mmHg（95%CI：-4.26，-0.03）。贝叶斯荟萃分析显示，干预组收缩压和舒张压分别降低 3.34mmHg（95%CrI：-5.15，-1.56）和 2.14mmHg（95%CrI：-3.79，-0.50）。亚组分析支持只要健康孕妇参与运动，其血压就会得到轻微调节，而高血压易感孕妇的血压则显著降低。
孕期运动干预有利于降低或使血压正常化，本研究为后续研究提供了线索。
