Carrillo Oscar, Saenz Daniela, Barrientos Edwin
Department of Research, Universidad de San Carlos de Guatemala, Guatemala City, GTM.
Department of Medical Research, Universidad Francisco Marroquín, Guatemala City, GTM.
Cureus. 2025 Aug 4;17(8):e89371. doi: 10.7759/cureus.89371. eCollection 2025 Aug.
Endometrial adenocarcinoma frequently metastasizes to distant organs, with the lungs being a common site. Pulmonary metastases typically present as multiple nodules. However, solitary lesions are uncommon and may offer surgical opportunities. This case report describes a 42-year-old woman with a history of stage IV endometrial adenocarcinoma who was found to have a solitary hypermetabolic pulmonary nodule on surveillance by Positron Emission Tomography/Computed Tomography (PET-CT). She underwent a uniportal video-assisted thoracoscopic surgery (VATS) anatomical segmentectomy of the left lingular segments (S4-S5). Histopathology confirmed moderately differentiated metastatic adenocarcinoma of endometrial origin with clear surgical margins. This case highlights the feasibility and oncologic effectiveness of uniportal VATS segmentectomy in managing isolated pulmonary metastases from gynecologic malignancies, emphasizing the role of minimally invasive surgery in selected patients.
子宫内膜腺癌常转移至远处器官，肺部是常见转移部位。肺转移瘤通常表现为多发结节。然而，孤立性病变并不常见，可能提供手术机会。本病例报告描述了一名42岁有IV期子宫内膜腺癌病史的女性，其在正电子发射断层扫描/计算机断层扫描（PET-CT）监测中发现有一个孤立的高代谢肺结节。她接受了单孔电视辅助胸腔镜手术（VATS）下左舌段（S4-S5）的解剖性肺段切除术。组织病理学证实为起源于子宫内膜的中分化转移性腺癌，手术切缘清晰。本病例突出了单孔VATS肺段切除术在处理妇科恶性肿瘤孤立性肺转移中的可行性和肿瘤学疗效，强调了微创手术在特定患者中的作用。
