Uniportal Video-Assisted Thoracoscopic Surgery (VATS) Lingular Segmentectomy for Solitary Pulmonary Metastasis From Endometrial Carcinoma: A Case Report.

Endometrial adenocarcinoma frequently metastasizes to distant organs, with the lungs being a common site. Pulmonary metastases typically present as multiple nodules. However, solitary lesions are uncommon and may offer surgical opportunities. This case report describes a 42-year-old woman with a history of stage IV endometrial adenocarcinoma who was found to have a solitary hypermetabolic pulmonary nodule on surveillance by Positron Emission Tomography/Computed Tomography (PET-CT). She underwent a uniportal video-assisted thoracoscopic surgery (VATS) anatomical segmentectomy of the left lingular segments (S4-S5). Histopathology confirmed moderately differentiated metastatic adenocarcinoma of endometrial origin with clear surgical margins. This case highlights the feasibility and oncologic effectiveness of uniportal VATS segmentectomy in managing isolated pulmonary metastases from gynecologic malignancies, emphasizing the role of minimally invasive surgery in selected patients.