Haarbauer-Krupa Juliet, Barber Jason, Temkin Nancy, Nelson Lindsay D, Wallace Tracey, Barnett Nathan
Division of Injury Prevention, Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, Atlanta, Georgia, USA.
Department of Neurological Surgery, University of Washington, Seattle, Washington, USA.
Neurotrauma Rep. 2025 Aug 13;6(1):651-659. doi: 10.1177/08977151251362109. eCollection 2025.
Research on mild traumatic brain injury (mTBI) and its impact on young adults is limited, despite this being an important time in their lives to work toward independence and career development. We analyzed data on 663 persons aged 17-29 years old with mTBI (i.e., TBI with Glasgow Coma Scale scores 13-15) and 170 controls who did not experience an injury from the multicenter, Transforming Research and Clinical Knowledge in TBI study. We assessed participants with mTBI, subdivided into those with computed tomography (CT) evidence of TBI (CT+) and those without (CT-), at 12 months post-injury with measures to examine symptom persistence, work and school status, and functional outcomes. Results indicated differences between mTBI and control participants related to return-to-work, return-to-school, and persistent symptoms. Those in the mTBI group were more likely to experience adverse symptoms and detrimental functional effects compared with controls at 12-months post-injury. However, other factors that may not have been measured could have contributed to these outcomes. Young adults are in a transition period where they are working to achieve independence and to establish careers; however, if they sustain a TBI, they, their families, and their medical providers may not understand how the injury contributes to their outcomes, and they may also have limited experience in seeking resources for care. Outcomes for mTBI could also disrupt their career and life trajectories, making this an important area for further investigation and intervention.
尽管轻度创伤性脑损伤(mTBI)及其对年轻人的影响在他们努力实现独立和职业发展的人生重要阶段中具有重要意义,但相关研究却很有限。我们分析了来自多中心的“TBI研究中的转化研究与临床知识”研究中663名年龄在17至29岁之间的mTBI患者(即格拉斯哥昏迷量表评分为13 - 15分的TBI患者)以及170名未受伤的对照组的数据。我们在受伤后12个月对mTBI患者进行了评估,将其细分为有计算机断层扫描(CT)证据显示TBI的患者(CT +)和无此证据的患者(CT -),通过多种测量方法来检查症状持续情况、工作和学习状态以及功能结局。结果表明,mTBI患者与对照组在重返工作、重返学校和持续症状方面存在差异。与对照组相比,mTBI组的患者在受伤后12个月时更有可能出现不良症状和有害的功能影响。然而,其他可能未被测量的因素也可能导致了这些结果。年轻人正处于努力实现独立和建立职业生涯的过渡阶段;然而,如果他们遭受了TBI,他们自己、他们的家人以及他们的医疗服务提供者可能并不了解该损伤如何影响他们的结局,而且他们在寻求护理资源方面的经验也可能有限。mTBI的结局也可能扰乱他们的职业和生活轨迹,这使得这成为一个需要进一步研究和干预的重要领域。