Yu Qiaolin, Yao Rong, Lei Limei, Shao Xiaoli, Huang Leilei, Xie Fanghui, Zhou Yan, Zhang Ting, Li Yuanyuan, Long Xiang, Zhang Miao, Yang Xiaoyi, Hu Yinping
The Frist Department of Tuberculosis, the Public Health Clinical Center of ChengDu, Jinjiang District, Chengdu, Sichuan, China.
The Second Department of Tuberculosis, the Public Health Clinical Center of ChengDu, Jinjiang District, Chengdu, Sichuan, China.
PLoS One. 2025 Sep 8;20(9):e0331700. doi: 10.1371/journal.pone.0331700. eCollection 2025.
Malnutrition is a significant risk factor contributing to the progression of the elderly with pulmonary tuberculosis (TB). This study aimed to evaluate the nutritional status of the elderly with pulmonary TB using the Mini Nutritional Assessment (MNA) and explore the relationship between their nutritional status and physical function.
This was a cross-sectional survey study. Data collection was from July 2023 to March 2024. 532 the elderly with pulmonary TB who were admitted to a tertiary infectious disease hospital in Chengdu were included in this analysis. The nutritional status of the patients was evaluated using MNA, and they were divided into well-nourished group (≥24 points) and abnormal-nourished group (<24 points). This study assessed physical function using the Berg Balance Scale (BBS), the Timed Up and Go test (TUG), and the Five-Times-Sit-to-Stand Test (FTSST). Clinical data and physical function of the two groups were compared, and the correlation between nutritional score and physical function was analyzed.
There were 109 cases (20.5%) in well-nourished group and 423 cases (79.5%) in abnormal-nourished group. Compared with well-nourished group, the abnormal group showed a decrease in the BBS scores [(52.55 ± 7.10) vs (43.20 ± 16.29), p < 0.05], and an increase in the TUG [9.00 (7.00, 10.00) vs 9.00 (7.40, 12.00), p < 0.05] and the FTSST [12.00 (9.00, 14.75) vs 15.00 (10.00, 20.10), p < 0.05]. Correlation analysis showed that the nutritional score of patients was positively correlated with the BBS scores (r = 0.474, p < 0.001), and negatively correlated with the TUG (r = -0.200, p < 0.001) and the FTSST (r = -0.501, p < 0.001).
Malnutrition is common in the elderly with pulmonary TB. Nutritional status in these patients is associated with the BBS scores, the TUG, and the FTSST.
营养不良是导致老年肺结核患者病情进展的重要危险因素。本研究旨在使用微型营养评定法（MNA）评估老年肺结核患者的营养状况，并探讨其营养状况与身体功能之间的关系。
这是一项横断面调查研究。数据收集时间为2023年7月至2024年3月。纳入了成都一家三级传染病医院收治的532例老年肺结核患者进行分析。使用MNA评估患者的营养状况，并将其分为营养良好组（≥24分）和营养异常组（<24分）。本研究使用伯格平衡量表（BBS）、计时起立行走测试（TUG）和五次坐立试验（FTSST）评估身体功能。比较两组的临床数据和身体功能，并分析营养评分与身体功能之间的相关性。
营养良好组有109例（20.5%），营养异常组有423例（79.5%）。与营养良好组相比，营养异常组的BBS评分降低[（52.55±7.10）对（43.20±16.29），p<0.05]，TUG增加[9.00（7.00，10.00）对9.00（7.40，12.00），p<0.05]，FTSST增加[12.00（9.00，14.75）对15.00（10.00，20.10），p<0.05]。相关性分析表明，患者的营养评分与BBS评分呈正相关（r=0.474，p<0.001），与TUG呈负相关（r=-0.200，p<0.001），与FTSST呈负相关（r=-0.501，p<0.001）。
营养不良在老年肺结核患者中很常见。这些患者的营养状况与BBS评分、TUG和FTSST相关。
