Matsui Kazuko, Niwa Makoto, Watanabe Atsushi, Watanabe Chuichi, Teramae Norio
Frontier Laboratories Ltd., 4-16-20, Saikon, Koriyama, Fukushima, 963-8862, Japan.
Graduate School of Environmental Studies, Tohoku University, Aoba, Sendai, 980-8572, Japan.
Anal Sci. 2025 Sep 8. doi: 10.1007/s44211-025-00845-2.
Biomass-based polymers such as poly(lactic acid) (PLA) have attracted much attention, because they are renewable, biocompatible, and nontoxic to the environment and have been used in various fields such as biomedical, agricultural, and food packaging industries. However, one of the common drawbacks of PLA-based materials is their low glass transition temperature in the amorphous state, while adding phenylphosphonic acid zinc salt (PPA-Zn) as a nucleating agent was found to be a promising method to improve the physical property of PLA. On the other hand, degradation of PLA-based materials in the environment may cause the pollution from the metal of a nucleating agent in PLA and quantification of nucleating agents in polymers is of interest. Polar phosphonic acid, a ligand in PPA-Zn, is not favorable for the analysis by gas chromatography/mass spectrometry (GC/MS). Such compounds containing polar groups are known to be effectively analyzed by GC/MS in combination with thermally assisted methylation reaction. In this study, we report on determination of PPA-Zn in PLA by coupling thermally assisted methylation with pyrolysis-GC/MS.
基于生物质的聚合物，如聚乳酸（PLA），已引起广泛关注，因为它们可再生、具有生物相容性且对环境无毒，已被应用于生物医学、农业和食品包装等各个领域。然而，基于PLA的材料的一个常见缺点是其非晶态下的玻璃化转变温度较低，而添加苯基膦酸锌盐（PPA-Zn）作为成核剂被认为是改善PLA物理性能的一种有前景的方法。另一方面，基于PLA的材料在环境中的降解可能会导致PLA中成核剂金属的污染，聚合物中成核剂的定量分析备受关注。极性膦酸是PPA-Zn中的一种配体，不利于通过气相色谱/质谱联用（GC/MS）进行分析。已知这类含极性基团的化合物可通过GC/MS结合热辅助甲基化反应进行有效分析。在本研究中，我们报道了通过热辅助甲基化与热解-GC/MS联用测定PLA中的PPA-Zn。
