Wang Nu, Zhu Yu, Zhang Ye
Department of Respiratory and Critical Care Medicine, Hejiang People's Hospital, Luzhou City, Sichuan Province, China.
Medicine (Baltimore). 2025 Sep 5;104(36):e44228. doi: 10.1097/MD.0000000000044228.
Chronic obstructive pulmonary disease (COPD) requires effective management that often depends on the knowledge level of primary family caregivers. This study assessed caregiver knowledge using a validated scale and identified key factors associated with higher COPD knowledge. A cross-sectional survey was conducted from April 2020 to January 2024 at a tertiary hospital in Southwest China. A total of 726 primary family caregivers of recently discharged COPD patients completed the general information questionnaire and the COPD health knowledge scale. Participants were categorized into high and low knowledge groups based on a predefined cutoff score of 21, reflecting adequate disease-related knowledge. Multivariate logistic regression was used to identify independent predictors. Higher educational attainment (OR = 126.568, 95% CI: 37.489-427.302, P < .001), receipt of COPD-specific health education (OR = 114.731, 95% CI: 33.426-393.804, P < .001), and older age (OR = 1.058 per year increase, 95% CI: 1.025-1.093, P < .001) were significantly associated with higher COPD knowledge. The predictive model showed excellent discrimination (C-index = 0.995) and good calibration, although external validation is needed to confirm its generalizability. This study identified education level, health education exposure, and age as key factors influencing caregiver COPD knowledge. The use of a fixed cutoff score enhances interpretability and external comparability. Targeted educational interventions may improve caregiver knowledge and support better disease management. Further longitudinal and interventional studies are warranted to confirm causal relationships.
慢性阻塞性肺疾病（COPD）需要有效的管理，而这通常取决于家庭主要照料者的知识水平。本研究使用经过验证的量表评估照料者的知识水平，并确定与较高COPD知识水平相关的关键因素。2020年4月至2024年1月在中国西南部一家三级医院进行了一项横断面调查。共有726名近期出院的COPD患者的家庭主要照料者完成了一般信息问卷和COPD健康知识量表。根据预先设定的21分的临界值将参与者分为高知识组和低知识组，该临界值反映了足够的疾病相关知识。采用多变量逻辑回归来确定独立预测因素。较高的教育程度（OR = 126.568，95%CI：37.489 - 427.302，P <.001）、接受COPD特定健康教育（OR = 114.731，95%CI：33.426 - 393.804，P <.001）和年龄较大（每年增加的OR = 1.058，95%CI：1.025 - 1.093，P <.001）与较高的COPD知识水平显著相关。该预测模型显示出出色的区分度（C指数 = 0.995）和良好的校准度，不过需要外部验证来确认其可推广性。本研究确定教育水平、健康教育接触情况和年龄是影响照料者COPD知识的关键因素。使用固定的临界值可提高可解释性和外部可比性。有针对性的教育干预可能会提高照料者的知识水平，并支持更好的疾病管理。有必要进行进一步的纵向和干预性研究以确认因果关系。
