• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

慢性阻塞性肺疾病(COPD)合并认知障碍:当前认识、危险因素、对临床实践的影响及建议干预措施。

Comorbid Cognitive Impairment in Chronic Obstructive Pulmonary Disease (COPD): Current Understanding, Risk Factors, Implications for Clinical Practice, and Suggested Interventions.

机构信息

Department of Respiratory Care, College of Applied Medical Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia.

出版信息

Medicina (Kaunas). 2023 Apr 8;59(4):732. doi: 10.3390/medicina59040732.

DOI:10.3390/medicina59040732
PMID:37109690
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10146750/
Abstract

Cognitive impairment is a common comorbidity in patients with COPD, significantly impacting health and clinical outcomes. Yet it remains under investigated and is largely overlooked. Although the exact cause of cognitive impairment in patients with COPD is still unclear, factors such as hypoxemia, vascular disease, smoking, exacerbation, and physical inactivity have been suggested. While international guidelines recommend identifying comorbidity in patients with COPD, such as cognitive impairment, cognitive assessment is not yet part of the routine assessment. Unidentified cognitive deficits in patients with COPD may have severe impacts on clinical management, resulting in an inability to maintain functional independence, poor self-management, and a greater dropout from pulmonary rehabilitation programs. There is a need to consider cognitive screening as a part of COPD assessment to promote early detection of cognitive impairment. Recognizing cognitive impairment early in the course of the illness allows the development of individualized interventions to meet patients' needs and improve clinical outcomes. Pulmonary rehabilitation should be tailored to cognitively impaired patients with COPD to maximize the benefits and minimize the incompletion rate.

摘要

认知障碍是 COPD 患者常见的合并症,严重影响健康和临床结局。然而,它仍然未被充分研究,在很大程度上被忽视了。虽然 COPD 患者认知障碍的确切原因尚不清楚,但缺氧、血管疾病、吸烟、恶化和身体不活动等因素已被提出。尽管国际指南建议识别 COPD 患者的合并症,如认知障碍,但认知评估尚未成为常规评估的一部分。未被识别的 COPD 患者认知缺陷可能对临床管理产生严重影响,导致无法保持功能独立性、自我管理能力差以及从肺康复计划中辍学率更高。需要将认知筛查视为 COPD 评估的一部分,以促进认知障碍的早期发现。在疾病早期识别认知障碍,可以制定个性化干预措施来满足患者的需求并改善临床结局。应根据 COPD 患者的认知障碍情况调整肺康复计划,以最大限度地提高效益并降低完成率。

相似文献

1
Comorbid Cognitive Impairment in Chronic Obstructive Pulmonary Disease (COPD): Current Understanding, Risk Factors, Implications for Clinical Practice, and Suggested Interventions.慢性阻塞性肺疾病(COPD)合并认知障碍:当前认识、危险因素、对临床实践的影响及建议干预措施。
Medicina (Kaunas). 2023 Apr 8;59(4):732. doi: 10.3390/medicina59040732.
2
Cognitive impairment in chronic obstructive pulmonary disease: disease burden, determinants and possible future interventions.慢性阻塞性肺疾病患者的认知障碍:疾病负担、决定因素及可能的未来干预措施。
Expert Rev Respir Med. 2018 Dec;12(12):1061-1074. doi: 10.1080/17476348.2018.1533405. Epub 2018 Oct 14.
3
Roles of Omega-3 Polyunsaturated Fatty Acids in Managing Cognitive Impairment in Chronic Obstructive Pulmonary Disease: A Review.ω-3 多不饱和脂肪酸在慢性阻塞性肺疾病认知障碍管理中的作用:综述。
Nutrients. 2023 Oct 13;15(20):4363. doi: 10.3390/nu15204363.
4
The impact of cognitive impairment on self-management in chronic obstructive pulmonary disease: A systematic review.认知障碍对慢性阻塞性肺疾病自我管理的影响:一项系统综述。
Respir Med. 2017 Aug;129:130-139. doi: 10.1016/j.rmed.2017.06.006. Epub 2017 Jun 15.
5
Cognitive Impairment in Chronic Obstructive Pulmonary Disease (COPD): Possible Utility of Marine Bioactive Compounds.慢性阻塞性肺疾病(COPD)认知障碍:海洋生物活性化合物的可能效用。
Mar Drugs. 2018 Sep 4;16(9):313. doi: 10.3390/md16090313.
6
Cognitive function during exacerbations of chronic obstructive pulmonary disease.慢性阻塞性肺疾病加重期的认知功能。
Intern Med J. 2019 Oct;49(10):1307-1312. doi: 10.1111/imj.14259.
7
Association of chronic obstructive pulmonary disease with mild cognitive impairment and dementia.慢性阻塞性肺疾病与轻度认知障碍和痴呆的关系。
Curr Opin Pulm Med. 2018 Mar;24(2):173-178. doi: 10.1097/MCP.0000000000000458.
8
Chronic Obstructive Pulmonary Disease as a Risk Factor for Cognitive Dysfunction: A Meta-Analysis of Current Studies.慢性阻塞性肺疾病作为认知功能障碍的一个危险因素:当前研究的荟萃分析
J Alzheimers Dis. 2016 Feb 27;52(1):101-11. doi: 10.3233/JAD-150735.
9
Cognitive screening in chronic obstructive pulmonary disease: patient's perspectives.慢性阻塞性肺疾病的认知筛查:患者的观点。
Disabil Rehabil. 2020 May;42(9):1233-1239. doi: 10.1080/09638288.2018.1519046. Epub 2019 Jan 26.
10
Cognitive dysfunction among patients in chronic obstructive pulmonary disease: Effects of exacerbation and long-term oxygen therapy.慢性阻塞性肺疾病患者的认知功能障碍:加重期和长期氧疗的影响。
Clin Respir J. 2020 Dec;14(12):1137-1143. doi: 10.1111/crj.13250. Epub 2020 Aug 24.

引用本文的文献

1
Demographic and educational factors associated with COPD knowledge among primary family caregivers: A cross-sectional study at a tertiary hospital.初级家庭照顾者中与慢性阻塞性肺疾病(COPD)知识相关的人口统计学和教育因素:一项在三级医院开展的横断面研究
Medicine (Baltimore). 2025 Sep 5;104(36):e44228. doi: 10.1097/MD.0000000000044228.
2
Comparative effects of square-stepping and strengthening exercises on cognitive and balance functions in chronic obstructive pulmonary disease: a randomized clinical trial.方步训练与强化训练对慢性阻塞性肺疾病患者认知及平衡功能的比较效果:一项随机临床试验
PeerJ. 2025 Jul 30;13:e19792. doi: 10.7717/peerj.19792. eCollection 2025.
3
Mechanisms of cognitive impairment in arterial hypertension.动脉高血压认知功能障碍的机制。
World J Psychiatry. 2025 Jul 19;15(7):106597. doi: 10.5498/wjp.v15.i7.106597.
4
Mesenchymal stem cell-derived exosomes-a promising therapeutic approach to improve neurocognitive disorders in chronic obstructive pulmonary disease.间充质干细胞衍生的外泌体——一种改善慢性阻塞性肺疾病神经认知障碍的有前景的治疗方法。
Stem Cell Res Ther. 2025 Jun 20;16(1):314. doi: 10.1186/s13287-025-04457-5.
5
A biopsychosocial analysis of risk factors for persistent physical, cognitive, and psychological symptoms among previously hospitalized post-COVID-19 patients.对新冠疫情后曾住院患者持续存在身体、认知和心理症状的风险因素进行的生物心理社会分析。
Sci Rep. 2025 Apr 24;15(1):14234. doi: 10.1038/s41598-025-99176-5.
6
Abnormal Brain Functional Connectivity in Patients with Chronic Obstructive Pulmonary Disease and Correlations with Clinical and Cognitive Parameters.慢性阻塞性肺疾病患者的脑功能连接异常及其与临床和认知参数的相关性
Int J Chron Obstruct Pulmon Dis. 2025 Apr 5;20:971-985. doi: 10.2147/COPD.S505271. eCollection 2025.
7
Construction and evaluation of nomogram for risk prediction of cognitive impairment in chronic obstructive pulmonary disease comorbidity.慢性阻塞性肺疾病合并症认知障碍风险预测列线图的构建与评估
BMC Psychol. 2025 Mar 19;13(1):273. doi: 10.1186/s40359-025-02516-3.
8
Managing cognitive impairment in patients with chronic obstructive pulmonary disease (COPD) in Saudi Arabia: what are the current practices?沙特阿拉伯慢性阻塞性肺疾病(COPD)患者认知障碍的管理:当前的做法是什么?
Ann Med. 2025 Dec;57(1):2413924. doi: 10.1080/07853890.2024.2413924. Epub 2025 Jan 28.
9
Healthcare Workers (HCWs)' Perceptions and Current Practice of Managing Cognitively Impaired Patients with Chronic Obstructive Pulmonary Disease (COPD).医护人员对慢性阻塞性肺疾病(COPD)认知障碍患者的管理认知与当前实践
Medicina (Kaunas). 2025 Jan 2;61(1):59. doi: 10.3390/medicina61010059.
10
The application effect of a pulmonary rehabilitation program based on empowerment theory for patients with COPD combined with heart failure.基于授权理论的肺康复方案在 COPD 合并心力衰竭患者中的应用效果。
Medicine (Baltimore). 2024 Oct 11;103(41):e40067. doi: 10.1097/MD.0000000000040067.

本文引用的文献

1
Automatic Detection of Cognitive Impairment with Virtual Reality.利用虚拟现实技术自动检测认知障碍
Sensors (Basel). 2023 Jan 16;23(2):1026. doi: 10.3390/s23021026.
2
Risk of dementia or cognitive impairment in COPD patients: A meta-analysis of cohort studies.慢性阻塞性肺疾病(COPD)患者患痴呆症或认知障碍的风险:队列研究的荟萃分析
Front Aging Neurosci. 2022 Sep 9;14:962562. doi: 10.3389/fnagi.2022.962562. eCollection 2022.
3
Risk of developing cognitive impairment on patients with chronic obstructive pulmonary disease: A systematic review.慢性阻塞性肺疾病患者认知障碍的发病风险:系统评价。
Medicine (Baltimore). 2022 Jun 24;101(25):e29235. doi: 10.1097/MD.0000000000029235.
4
Prevalence and Impact of Comorbidities in Individuals with Chronic Obstructive Pulmonary Disease: A Systematic Review.慢性阻塞性肺疾病患者合并症的患病率及影响:一项系统评价
Tuberc Respir Dis (Seoul). 2022 Jul;85(3):205-220. doi: 10.4046/trd.2021.0179. Epub 2022 May 27.
5
Progression to Dementia or Reversion to Normal Cognition in Mild Cognitive Impairment as a Function of Late-Onset Neuropsychiatric Symptoms.轻度认知障碍中迟发性神经精神症状与向痴呆进展或认知恢复正常的关系。
Neurology. 2022 May 24;98(21):e2132-e2139. doi: 10.1212/WNL.0000000000200256. Epub 2022 Mar 29.
6
Incidence of depression and antidepressant prescription in patients with COPD: A large UK population-based cohort study.慢性阻塞性肺疾病患者中抑郁症的发病率及抗抑郁药物处方情况:一项基于英国大规模人群的队列研究。
Respir Med. 2022 May;196:106804. doi: 10.1016/j.rmed.2022.106804. Epub 2022 Mar 12.
7
Metabolomics of COPD Pulmonary Rehabilitation Outcomes via Exhaled Breath Condensate.COPD 肺康复结局的呼出气冷凝物代谢组学研究
Cells. 2022 Jan 20;11(3):344. doi: 10.3390/cells11030344.
8
The interaction and pathogenesis between cognitive impairment and common cardiovascular diseases in the elderly.老年人认知障碍与常见心血管疾病之间的相互作用及发病机制。
Ther Adv Chronic Dis. 2022 Feb 2;13:20406223211063020. doi: 10.1177/20406223211063020. eCollection 2022.
9
Associations Between Cognitive Function, Balance, and Gait Speed in Community-Dwelling Older Adults with COPD.社区中老年 COPD 患者认知功能、平衡和步态速度之间的关联。
J Geriatr Phys Ther. 2023;46(1):46-52. doi: 10.1519/JPT.0000000000000323. Epub 2021 Jul 29.
10
GOLD 2021 guidelines for COPD - what's new and why.慢性阻塞性肺疾病全球倡议(GOLD)2021年慢性阻塞性肺疾病指南——有哪些新内容及原因。
Adv Respir Med. 2021;89(3):344-346. doi: 10.5603/ARM.a2021.0015. Epub 2021 Apr 21.