Khalil Muhammad Ashhad Ullah, Abbasi Sajid, Nawaz Reena, Rashid Noor Ul Ain, Ghazi Muhammad Anas, Patujo Yassar Hussain, Mughal Rameez Ahmed, Liaquat Faisal, Raza Hafiz Ali
Urology, Institute of Kidney Diseases, Hayatabad Medical Complex, Peshawar, PAK.
Urology, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, PAK.
Cureus. 2025 Aug 8;17(8):e89640. doi: 10.7759/cureus.89640. eCollection 2025 Aug.
Bladder outlet obstruction (BOO) due to benign prostatic hyperplasia (BPH) is a common urological condition in aging men, often requiring surgical intervention for symptom relief.
To evaluate the therapeutic efficacy and complication profile of monopolar transurethral resection of the prostate (TURP) in patients with BOO.
This descriptive observational study was conducted at the Department of Urology, Hayatabad Medical Complex, Peshawar, and Akhtar Saeed Trust Hospital, Lahore, from August 2022 to July 2024. A total of 518 male patients aged ≥ 50 years with BOO secondary to BPH underwent monopolar TURP. Preoperative, intraoperative, and postoperative variables were collected using a standardized proforma. Functional outcomes, including International Prostate Symptom Score (IPSS), maximum urinary flow rate (Qmax), and post-void residual volume (PVR), were assessed at baseline and one, six, and 12 months postoperatively. Complication rates and predictors were also analyzed.
Mean age was 68.42 ± 7.85 years. Significant improvement was observed in IPSS (from 23.74 ± 4.96 to 7.82 ± 2.81), Qmax (from 7.89 ± 2.11 mL/sec to 17.50 ± 4.67 mL/sec), and PVR (from 126.40 ± 34.70 mL to 30.10 ± 16.87 mL) at 12 months (p < 0.001). Early complications included hematuria in 42 patients (8.11%), UTI in 61 (11.78%), and TUR syndrome in six (1.16%). Late complications included urethral stricture (3.67%) and bladder neck contracture (2.12%).
Monopolar TURP is an effective and safe surgical option for managing BOO due to BPH in resource-limited settings.
良性前列腺增生（BPH）所致膀胱出口梗阻（BOO）是老年男性常见的泌尿系统疾病，常需手术干预以缓解症状。
评估单极经尿道前列腺切除术（TURP）治疗BOO患者的疗效及并发症情况。
本描述性观察性研究于2022年8月至2024年7月在白沙瓦哈亚塔巴德医疗中心泌尿外科及拉合尔阿赫塔尔·赛义德信托医院开展。共有518例年龄≥50岁、因BPH继发BOO的男性患者接受了单极TURP手术。术前、术中和术后变量通过标准化表格收集。在基线、术后1个月、6个月和12个月评估功能结局，包括国际前列腺症状评分（IPSS）、最大尿流率（Qmax）和残余尿量（PVR）。还分析了并发症发生率及预测因素。
平均年龄为68.42±7.85岁。术后12个月时，IPSS（从23.74±4.96降至7.82±2.81）、Qmax（从7.89±2.11 mL/秒增至17.50±4.67 mL/秒）和PVR（从126.40±34.70 mL降至30.10±16.87 mL）均有显著改善（p<0.001）。早期并发症包括42例（8.11%）血尿、61例（11.78%）尿路感染和6例（1.16%）TUR综合征。晚期并发症包括尿道狭窄（3.67%）和膀胱颈挛缩（2.12%）。
在资源有限的环境中，单极TURP是治疗BPH所致BOO的有效且安全的手术选择。
