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利用羟基磷灰石(STIIM)的多功能性进行微创面部提升。

Minimally Invasive Facial Lifting Using the Versatility of Calcium Hydroxyapatite (STIIM).

作者信息

Saavedra Deus Barbara, Viana Renata

机构信息

Independent Researcher, São Paulo, Brazil.

出版信息

J Cosmet Dermatol. 2025 Sep;24(9):e70427. doi: 10.1111/jocd.70427.

Abstract

INTRODUCTION

Facial aging is a multifactorial process characterized by skin laxity, volume loss, and collagen degradation. Calcium Hydroxyapatite (CaHA) is a versatile biostimulatory filler that can provide both structural support and collagen stimulation. This study evaluates a novel technique using CaHA with tailored dilutions for minimally invasive facial rejuvenation, focusing on key ligamentous structures.

OBJECTIVES

To assess the aesthetic outcomes, patient satisfaction, and safety profile of the technique using regionalized CaHA dilutions.

METHODS

A prospective, single-center study was conducted involving 20 subjects with facial laxity. CaHA injections were performed using three distinct dilution ratios protocols, targeting the zygomatic, temporal, and mandibular regions. Endpoints were evaluated through Face-Q questionnaires, GAIS, and standardized 2D and 3D imaging.

RESULTS

At 90 days, 94% of subjects reported aesthetic improvement, and the mean Face-Q Skin score increased from 43.2 ± 14.7 to 74.9 ± 14.7. These results were maintained at 360 days, with 94% of participants continuing to report improvement and a sustained FACE-Q Skin score of 77.2 ± 16.4. Investigator assessments confirmed long-term improvements, and 3D imaging showed persistent enhancement in facial contours. Adverse events were mild and self-limiting.

CONCLUSIONS

This CaHA-based technique offers a safe, minimally invasive facial lifting effect with sustained improvement over 12 months. Its effectiveness is enhanced by targeting facial ligaments and customizing dilution based on anatomical region.

摘要

引言

面部衰老是一个多因素过程,其特征为皮肤松弛、容量减少和胶原蛋白降解。羟基磷灰石(CaHA)是一种多功能生物刺激填充剂,可提供结构支撑并刺激胶原蛋白生成。本研究评估了一种使用经定制稀释的CaHA进行微创面部年轻化的新技术,重点关注关键韧带结构。

目的

评估使用区域化CaHA稀释技术的美学效果、患者满意度和安全性。

方法

进行了一项前瞻性单中心研究,纳入20名面部松弛的受试者。使用三种不同的稀释比例方案进行CaHA注射,分别针对颧骨、颞部和下颌区域。通过面部质量问卷(Face-Q)、全球美学改善量表(GAIS)以及标准化的二维和三维成像对终点指标进行评估。

结果

在90天时,94%的受试者报告美学改善,面部质量问卷皮肤评分均值从43.2±14.7提高到74.9±14.7。这些结果在360天时得以维持,94%的参与者继续报告有改善,面部质量问卷皮肤评分持续保持在77.2±16.4。研究者评估证实了长期改善效果,三维成像显示面部轮廓持续增强。不良事件轻微且为自限性。

结论

这种基于CaHA的技术提供了一种安全、微创的面部提升效果,在12个月内持续改善。通过针对面部韧带并根据解剖区域定制稀释,其效果得到增强。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab2e/12418901/5402aa74ade2/JOCD-24-e70427-g004.jpg

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