Perbeck L, Nyberg B, Thulin L, Tydén G
Clin Physiol. 1985 Dec;5(6):567-74. doi: 10.1111/j.1475-097x.1985.tb00769.x.
In sixteen patients subjected to intestinal surgery, the transport of sodium fluorescein (Na-F) was measured between the mucosal and serosal-muscular layers. Experiments were carried out in intestinal anastomosis by fluorescein flowmetry (FF). The blood-flow index of the mucosal layer was about twice the serosal-muscularis, per unit tissue volume. The temporal changes in fluorescence pattern from the two layers showed that more than 90% of Na-F, eliminated from the mucosal layer, was transported to the serosal-muscular layers. In six patients, in whom Na-F was instilled intraluminarily, fluorescence was seen on the outside of the intestine after 3 min. However, when the circulation was stopped before Na-F was instilled, no fluorescence was seen, this suggests that the transport was not only due to diffusion but also to convection. The results suggest that functional serially-coupled exchange vessels may exist within the intestinal wall, and that Na-F is transported both by convection and diffusion.
对16例接受肠道手术的患者，测量了荧光素钠（Na-F）在黏膜层和浆膜-肌层之间的转运。通过荧光素流速测定法（FF）在肠道吻合处进行实验。每单位组织体积，黏膜层的血流指数约为浆膜-肌层的两倍。两层荧光模式的时间变化表明，从黏膜层消除的Na-F中，超过90%被转运到浆膜-肌层。在6例经腔内注入Na-F的患者中，3分钟后在肠外可见荧光。然而，在注入Na-F之前停止循环时，则未见荧光，这表明转运不仅是由于扩散，还由于对流。结果表明，肠壁内可能存在功能性串联耦合交换血管，且Na-F通过对流和扩散进行转运。
