Cao Jenny Jia Ling, Reddy Yogesh N V
Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA.
Heart Fail Rev. 2025 Sep 9. doi: 10.1007/s10741-025-10553-8.
In contemporary clinical practice, pulmonary hypertension (PH) is most commonly caused by heart failure with preserved ejection fraction (HFpEF). This high prevalence of HFpEF-related PH has contributed to complexity in diagnosis and evaluation of PH in the context of other diseases such as the presence of risk factors for group 1 PH. In this review, we discuss emerging concepts guiding the evaluation, pathobiology, and treatment of PH in patients with HFpEF or HFpEF-associated risk factors.
在当代临床实践中，肺动脉高压（PH）最常见的病因是射血分数保留的心力衰竭（HFpEF）。HFpEF相关PH的高患病率导致在其他疾病背景下（如存在1组PH的危险因素）PH的诊断和评估变得复杂。在本综述中，我们讨论了指导HFpEF患者或HFpEF相关危险因素患者PH评估、病理生物学及治疗的新观念。
