Preece Patrick Daniel, Sahdev Varun, Davis Paul Gerard, Rees Rowland Wyn
Department of Urology, University Hospital Southampton, Southampton, UK.
Department of Urology, Geelong University Hospital, Geelong, VIC, Australia.
Basic Clin Androl. 2025 Sep 9;35(1):36. doi: 10.1186/s12610-025-00280-3.
To compare surgical and long-term patient-reported outcomes (PRO) between excisional (Nesbit) and incisional (Yachia) corporoplasty for correction of uncomplicated Peyronie's-related penile curvature in a large, single-surgeon cohort. A retrospective audit identified men who underwent Nesbit or Yachia corporoplasty (2015-2021). Operative data was extracted from records. A structured telephone survey captured long-term PRO.
The cohort comprised 101 men (Nesbit = 31, Yachia = 70). Nesbit patients were younger (55 vs 59.7 yr; p = 0.02) and had greater baseline curvature (55° vs 45°; p = 0.01). Every case was surgically successful (residual curvature < 20° in 100%, < 10° in 58% overall, p = 0.66). Yachia procedures were shorter (45 vs 71 min; p < 0.05) but required > 2 plications more often (41% vs 7%; p = 0.01). The PRO survey had a 74.3% response rate, with a median follow-up of 5 years. 'Patient Global Impression of Improvement' scores reflected strong improvement with median scores of 1 ("very much better") and 2 ("much better") in the Nesbit and Yachia groups respectively (p = 0.35). However, this perceived improvement did not translate uniformly into long-term satisfaction. Only 66.7% of respondents reported being "completely" or "mostly" satisfied with the overall outcome (p = 0.60). The most frequent cause of dissatisfaction was perceived penile shortening, reported by 85% of men. Erectile function declined postoperatively in 30% of Yachia and 15% of Nesbit patients (p = 0.03), though this is possibly confounded by the older age of the Yachia cohort. Bothersome curvature recurrence and post-operative cosmesis did not significantly impact satisfaction in either group.
Both Nesbit and Yachia corporoplasties provide effective and durable results with comparable long-term patient satisfaction. Regardless of technique, subjective reporting of penile shortening was particularly pervasive and was highly bothersome. This underscores the need for meticulous pre-operative counselling.
在一个大型单术者队列中,比较切除性(内斯比特)和切开性(亚希亚)阴茎成形术治疗单纯佩罗尼氏病相关阴茎弯曲的手术及长期患者报告结局(PRO)。一项回顾性审计确定了接受内斯比特或亚希亚阴茎成形术的男性(2015 - 2021年)。手术数据从记录中提取。通过结构化电话调查获取长期PRO。
该队列包括101名男性(内斯比特组 = 31例,亚希亚组 = 70例)。内斯比特组患者更年轻(55岁对59.7岁;p = 0.02),基线弯曲度更大(55°对45°;p = 0.01)。每例手术均成功(100%的患者残余弯曲度 < 20°,总体58%的患者 < 10°,p = 0.66)。亚希亚手术时间更短(45分钟对71分钟;p < 0.05),但更常需要 > 2次折叠(41%对7%;p = 0.01)。PRO调查的回复率为74.3%,中位随访时间为5年。“患者总体改善印象”评分反映出明显改善,内斯比特组和亚希亚组的中位评分分别为1(“好多了”)和2(“好多了”)(p = 0.35)。然而,这种感知到的改善并未一致转化为长期满意度。只有66.7%的受访者表示对总体结果“完全”或“大部分”满意(p = 0.60)。最常见的不满原因是感觉阴茎缩短,85%的男性报告了这一点。30%的亚希亚组患者和15%的内斯比特组患者术后勃起功能下降(p = 0.03),不过这可能与亚希亚组患者年龄较大有关。令人困扰的弯曲复发和术后美观问题对两组的满意度均无显著影响。
内斯比特和亚希亚阴茎成形术均能提供有效且持久的结果,长期患者满意度相当。无论采用何种技术,阴茎缩短的主观报告都特别普遍且令人困扰。这突出了术前细致咨询的必要性。