Khalifa Mateb Al, Ma Tianjun, Aljuaid Haya, Kim Siyong, Song William Y
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia, USA.
Department of Radiation Medicine, Northwell Health, Lake Success, New York, USA.
J Appl Clin Med Phys. 2025 Sep;26(9):e70247. doi: 10.1002/acm2.70247.
Real‑time magnetic resonance-guided radiation therapy (MRgRT) integrates MRI with a linear accelerator (Linac) for gating and adaptive radiotherapy, which requires robust image‑quality assurance over a large field of view (FOV). Specialized phantoms capable of accommodating this extensive FOV are therefore essential. This study compares the performance of four commercial MRI phantoms on a 0.35 T MR‑Linac.
Four phantoms: the IBA QUASAR Insight Phantom, the IBA QUASAR MRID Geometric Distortion Phantom, the MagPhan Phantom, and the Sun Nuclear Large Field MRI Distortion Phantom, were evaluated on a 0.35 T MR-Linac using the TRUFI clinical sequence. Mean distortions were measured at gantry angles from 0° to 360° in 30° increments. Clinical imaging parameters (signal-to-noise ratio, uniformity, resolution via modulation transfer function, laser alignment, and twist) were also assessed where applicable.
The QUASAR MRID Phantom enabled separate quantification of B and gradient-induced distortions but showed a notable vertical offset, which did not affect comparisons with other phantoms. Both the MagPhan and QUASAR Insight phantoms provided mean distortion measurements as well as additional imaging parameters (e.g., signal-to-noise ratio, uniformity, resolution). The Sun Nuclear Phantom exhibited higher overall distortion values.
All four phantoms successfully measured distortion at multiple gantry angles on a 0.35 T MR-Linac. The QUASAR MRID Phantom uniquely differentiated B from gradient distortions but required an offset adjustment. The MagPhan and QUASAR Insight phantoms offered comprehensive imaging metrics, while the Sun Nuclear Phantom exhibited relatively higher distortions.
实时磁共振引导放射治疗(MRgRT)将磁共振成像(MRI)与直线加速器(Linac)集成用于门控和自适应放射治疗,这需要在大视野(FOV)上进行稳健的图像质量保证。因此,能够适应这种大FOV的专用体模至关重要。本研究比较了四种商用MRI体模在0.35T MR-Linac上的性能。
使用TRUFI临床序列在0.35T MR-Linac上对四种体模进行评估:IBA QUASAR Insight体模、IBA QUASAR MRID几何畸变体模、MagPhan体模和太阳核大视野MRI畸变体模。在0°至360°的机架角度下,以30°增量测量平均畸变。还在适用的情况下评估了临床成像参数(信噪比、均匀性、通过调制传递函数的分辨率、激光对准和扭曲)。
QUASAR MRID体模能够分别量化B场和梯度诱导的畸变,但显示出明显的垂直偏移,这并不影响与其他体模的比较。MagPhan体模和QUASAR Insight体模都提供了平均畸变测量以及额外的成像参数(例如,信噪比、均匀性、分辨率)。太阳核体模表现出更高的整体畸变值。
所有四种体模都成功地在0.35T MR-Linac上的多个机架角度测量了畸变。QUASAR MRID体模独特地将B场畸变与梯度畸变区分开来,但需要进行偏移调整。MagPhan体模和QUASAR Insight体模提供了全面的成像指标,而太阳核体模表现出相对较高的畸变。