Luo Wei, Zhong Bao-Liang
Department of Psychology, Wuhan University, 430072 Wuhan, Hubei, China.
Department of Psychiatry, Wuhan Mental Health Center, 430012 Wuhan, Hubei, China.
Alpha Psychiatry. 2025 Jul 30;26(4):45405. doi: 10.31083/AP45405. eCollection 2025 Aug.
Depression is a common mental health problem that imposes a significant burden on both individuals and society. Numerous studies have shown that childhood abuse has a long-lasting detrimental effect on mental health, including the development of depression. This study reviews recent studies on the association between childhood abuse and depression, highlighting the robust causal link between childhood abuse and subsequent depression. The strength of this association varies depending on the type of abuse, with emotional abuse showing a particularly strong connection to depression. In addition, this narrative review examines the role of personality in the relationship between childhood abuse and depression. Evidence indicates that personality traits act as both mediators and moderators in this association, with neuroticism being particularly influential. Although available research evidence primarily consists of cross-sectional studies, which cannot determine the temporal sequence of childhood abuse, personality problems, and depression, the interrelations of these three variables provide a more comprehensive understanding of the etiology of depression. These insights lay the foundation for future longitudinal research and inform the development of more targeted preventive and therapeutic interventions in clinical psychiatry.
抑郁症是一种常见的心理健康问题,给个人和社会都带来了沉重负担。大量研究表明,童年期受虐对心理健康有长期的有害影响,包括抑郁症的发展。本研究回顾了近期关于童年期受虐与抑郁症之间关联的研究,强调了童年期受虐与随后发生的抑郁症之间确凿的因果联系。这种关联的强度因虐待类型而异,其中情感虐待与抑郁症的联系尤为紧密。此外,本篇叙述性综述考察了人格在童年期受虐与抑郁症关系中的作用。有证据表明,人格特质在这种关联中既起中介作用又起调节作用,其中神经质的影响尤为显著。尽管现有研究证据主要由横断面研究组成,无法确定童年期受虐、人格问题和抑郁症的时间顺序,但这三个变量之间的相互关系为更全面地理解抑郁症的病因提供了依据。这些见解为未来的纵向研究奠定了基础,并为临床精神病学中更具针对性的预防和治疗干预措施的制定提供了参考。