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真菌性颈内动脉动脉瘤的血管内治疗

Endovascular Treatment for Fungal Internal Carotid Artery Aneurysm.

作者信息

Irizato Naoki, Ozaki Tomohiko, Nakamura Hajime, Takagaki Masatoshi, Yamazaki Hiroki, Umehara Toru, Kishima Haruhiko

机构信息

Department of Neurosurgery, The University of Osaka Graduate School of Medicine, Suita, JPN.

Department of Neurosurgery, Osaka International Cancer Institute, Osaka, JPN.

出版信息

Cureus. 2025 Aug 9;17(8):e89684. doi: 10.7759/cureus.89684. eCollection 2025 Aug.

Abstract

Fungal cerebral aneurysms, particularly those resulting from direct invasion by fungal sinusitis, are rare and often fatal when involving the cavernous segment of the internal carotid artery (ICA). We present a case of a ruptured fungal ICA aneurysm caused by sinusitis, successfully treated with parent artery occlusion (PAO). In this case, an 80-year-old woman presented with right ptosis, facial pain, and cranial nerve III, IV, and VI palsies. Magnetic resonance imaging (MRI) and angiography revealed a spindle-shaped aneurysm in the cavernous segment of the right ICA with sphenoid sinus invasion. A balloon occlusion test demonstrated tolerance to ICA occlusion. Polymerase chain reaction analysis of sinus pus confirmed . Despite antifungal therapy and sinus irrigation, the aneurysm enlarged. While flow diversion was being planned, the aneurysm ruptured, causing massive epistaxis and shock. Emergent PAO using a double catheter technique was performed, preserving collateral flow via the anterior and posterior communicating arteries. Postoperatively, the patient had no new neurological deficits, with only residual oculomotor palsy. This case highlights the importance of early balloon occlusion testing in the management of fungal ICA aneurysms because of their high risk of rupture. Tight coil packing using a double catheter technique can minimize ischemic complications while preserving vital collateral circulation.

摘要

真菌性脑动脉瘤,尤其是由真菌性鼻窦炎直接侵袭导致的,较为罕见,累及颈内动脉(ICA)海绵窦段时往往致命。我们报告一例由鼻窦炎引起的破裂性真菌性ICA动脉瘤病例,采用经动脉闭塞(PAO)成功治疗。该病例中,一名80岁女性出现右眼睑下垂、面部疼痛及动眼神经、滑车神经和展神经麻痹。磁共振成像(MRI)和血管造影显示右ICA海绵窦段有一梭形动脉瘤并侵犯蝶窦。球囊闭塞试验显示对ICA闭塞耐受。鼻窦脓液的聚合酶链反应分析得以证实。尽管进行了抗真菌治疗和鼻窦冲洗,动脉瘤仍增大。在计划进行血流导向治疗时,动脉瘤破裂,导致大量鼻出血和休克。采用双导管技术紧急进行PAO,通过前、后交通动脉保留侧支血流。术后,患者无新的神经功能缺损,仅遗留动眼神经麻痹。该病例凸显了早期球囊闭塞试验在真菌性ICA动脉瘤治疗中的重要性,因其破裂风险高。采用双导管技术紧密填塞弹簧圈可在保留重要侧支循环的同时将缺血性并发症降至最低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3272/12416224/83b7a2039b1f/cureus-0017-00000089684-i01.jpg

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