True Anaphylaxis Due to an Amide-Type Local Agent: A Case Report.

Local anesthetics (LAs) are widely used to relieve surgical pain. Pure amide-type LAs rarely cause allergic reactions. Here, we present a case of anaphylaxis induced by multiple pure amide agents. We report a case of a 17-year-old girl with no history of allergies who was scheduled to undergo orthopedic surgery. She presented with anaphylactic symptoms after receiving peripheral nerve blocks. Postoperative allergy tests were positive for two kinds of amide-type LAs: pure lidocaine and ropivacaine. In conclusion, cross-reactivity should be considered in case of an allergic reaction to an amide-type agent.