生物导体计划：为基因组数据科学提供第三个十年的全面支持。

Bioconductor: Planning a third decade of comprehensive support for genomic data science.

作者信息

Carey Vincent J

机构信息

Channing Division of Network Medicine, Mass General Brigham, 181 Longwood Avenue, Boston, MA 02115, USA.

出版信息

Patterns (N Y). 2025 Jul 11;6(7):101319. doi: 10.1016/j.patter.2025.101319.

DOI:10.1016/j.patter.2025.101319

PMID:40926969

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12416078/

Abstract

This opinion piece discusses the Bioconductor project for open-source bioinformatics and the engineering concepts underlying its effectiveness to date. Since the inception of Bioconductor in 2002 with 15 software packages devoted to analysis of DNA microarrays, it has grown into an ecosystem of ∼3,000 packages contributed by more than 1,000 developers. Aspects of the history and commitments are reviewed here to contribute to thinking about the design and orchestration of future open-source software projects.

摘要

这篇观点文章讨论了用于开源生物信息学的Bioconductor项目以及迄今为止其有效性背后的工程概念。自2002年Bioconductor成立以来，当时有15个致力于DNA微阵列分析的软件包，如今它已发展成为一个由1000多名开发者贡献的约3000个软件包的生态系统。本文回顾了其历史和承诺的各个方面，以促进对未来开源软件项目的设计和编排的思考。