无症状造血干细胞移植和嵌合抗原受体T细胞治疗患者中SARS-CoV-2筛查的阳性率有限。
Limited yield of SARS-CoV-2 screening in asymptomatic hematopoietic cell transplant and chimeric antigen receptor T-cell therapy patients.
作者信息
Wilson Marie Hale, Krantz Elizabeth M, Pergam Steven A, Mielcarek Marco, Elgar Suni, Rosen Emily, Swetky Michelle, Liu Catherine, Hill Joshua A, Cohen Seth, McCulloch Denise J
机构信息
Quality Department, Fred Hutchinson Cancer Center, 1100 Fairview Ave N., Seattle, WA, 98109, USA.
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
出版信息
Antimicrob Steward Healthc Epidemiol. 2025 Aug 29;5(1):e195. doi: 10.1017/ash.2025.10112. eCollection 2025.
Early in the COVID-19 pandemic, screening was initiated in several settings to mitigate asymptomatic transmission of SARS-CoV-2. However, this practice was later discouraged by the Society for Healthcare Epidemiology of America. This single-center retrospective study demonstrates limited utility of SARS-CoV-2 screening tests in asymptomatic HCT and CAR T-cell patients.
在新冠疫情早期，在多个场所开展了筛查以减轻严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的无症状传播。然而，美国医疗保健流行病学学会后来不鼓励这种做法。这项单中心回顾性研究表明，SARS-CoV-2筛查检测在无症状造血干细胞移植（HCT）和嵌合抗原受体（CAR）T细胞患者中的效用有限。
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