Stockert M, De Robertis E
Eur J Pharmacol. 1985 Dec 17;119(3):255-7. doi: 10.1016/0014-2999(85)90306-1.
In rats, 35 days after ovariectomy, the number of [3H]imipramine binding sites increased more than 200% in striatum, hippocampus and hypothalamus but it did not change in cerebral cortex and brain-stem. Estradiol-17 beta acting in vitro inhibited [3H]imipramine binding in control membranes of striatum, hippocampus and hypothalamus, but not in the same regions from ovariectomized rats.
