Mowery Jenna L, Chen Jixin
Department of Chemistry and Biochemistry, Nanoscale & Quantum Phenomena Institute, Ohio University, Athens, Ohio 45701, United States.
J Phys Chem C Nanomater Interfaces. 2024 Oct 3;128(39):16291-16301. doi: 10.1021/acs.jpcc.4c04847. Epub 2024 Sep 20.
Carbon-based quantum dots (CQDs) have been around for a few decades. Low cell toxicity, good water solubility, excellent and tunable fluorescence properties, and the ability to dope and modify the surface of these CQDs make them an incredible choice for the visualization and treatment of various cancers. This perspective analyzes some recent progress on size-color correlation, modification, and cancer treatment applications of CQDs. Synthesis and modification of CQDs to make them more efficient and more biocompatible are essential to their bioapplications.
碳基量子点(CQDs)已经存在了几十年。低细胞毒性、良好的水溶性、优异且可调节的荧光特性,以及对这些CQDs进行掺杂和表面修饰的能力,使其成为可视化和治疗各种癌症的绝佳选择。本文综述了CQDs在尺寸-颜色相关性、修饰以及癌症治疗应用方面的一些最新进展。对CQDs进行合成和修饰以使其更高效、更具生物相容性,对其生物应用至关重要。