Farajzadeh Mir Ali, Hallaji Zahra, Pezhhanfar Sakha, Afshar Mogaddam Mohammad Reza
Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz Tabriz Iran
Engineering, Faculty, Near East University 99138 Nicosia, North Cyprus Mersin 10 Turkey.
RSC Adv. 2025 Sep 8;15(39):32328-32336. doi: 10.1039/d5ra03198b. eCollection 2025 Sep 5.
This study focuses on developing an analytical method to efficiently extract and concentrate several adipate and phthalate plasticizers that can migrate from plastic packaging into various wound disinfectants. The study employed an approach that combined dispersive micro solid phase extraction with dispersive liquid-liquid microextraction using ZIF-4 as an adsorbent. The adsorbent was thoroughly characterized to understand its properties. The microextraction step concentrated the target compounds for analysis using gas chromatography. After plasticizer adsorption onto ZIF-4, the analytes were desorbed using acetonitrile. The method demonstrated good performance by high extraction recoveries (61-95%) and enrichment factors (305-475), low detection (0.16-0.28 μg L) and quantification (0.54-0.93 μg L) limits, and good precision (relative standard deviation less than 7% for intra- and inter-day precisions).
本研究着重于开发一种分析方法，以有效提取和浓缩几种可从塑料包装迁移至各种伤口消毒剂中的己二酸酯和邻苯二甲酸酯类增塑剂。该研究采用了一种方法，即将分散微固相萃取与以ZIF-4作为吸附剂的分散液液微萃取相结合。对该吸附剂进行了全面表征以了解其性质。微萃取步骤对目标化合物进行浓缩，以便使用气相色谱法进行分析。增塑剂吸附到ZIF-4上后，使用乙腈对分析物进行解吸。该方法表现出良好的性能，具有较高的萃取回收率（61-95%）和富集因子（305-475）、较低的检测限（0.16-0.28 μg/L）和定量限（0.54-0.93 μg/L），以及良好的精密度（日内和日间精密度的相对标准偏差均小于7%）。
