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[下丘脑腹内侧核、室旁核和背内侧核对心脏作用的机制]

[Mechanism of the effect of the ventromedial, paraventricular and dorsomedial nuclei of the hypothalamus on the heart].

作者信息

Sikharulidze A I, Beridze K P

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1985 Dec;71(12):1495-9.

PMID:4092772
Abstract

The influence of electrical stimulation of ventromedial, paraventricular and dorsomedial nuclei of the hypothalamus on polycardiographic data and on the serotonin level in the blood was studied in anesthetized rabbits as well as the unit activity of the above nuclei. The nuclei of the hypothalamus seem to be involved in the change of the myocardium functional state. The role of the serotonin content change in the blood was shown in making these nuclei influence the heart. Neuropharmacological analysis revealed the role of the adrenergic substrate of rostral part of the reticular formation in actualization of the hypothalamo-cardial effects. Pressor, depressor and "neutral" neurons of the above hypothalamic nuclei are identified.

摘要

在麻醉兔身上研究了下丘脑腹内侧核、室旁核和背内侧核的电刺激对多导心电图数据和血液中血清素水平的影响,以及上述核团的单位活动。下丘脑核似乎参与了心肌功能状态的改变。血液中血清素含量变化在使这些核团影响心脏方面的作用得到了证实。神经药理学分析揭示了网状结构 Rostral 部分的肾上腺素能底物在实现下丘脑 - 心脏效应中的作用。确定了上述下丘脑核团的升压、降压和“中性”神经元。

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