Paolantonio Michele, De Ninis Paolo, Santamaria Pasquale, Balice Giuseppe, Serroni Matteo, Sinjari Bruna, Frisone Alessio, Di Gregorio Stefania, Romano Luigi, Murmura Giovanna, Femminella Beatrice
Department of Innovative Technologies in Medicine & Dentistry, "G. D'Annunzio" University, Via Dei Vestini 31, Chieti, Italy.
"Luisa D'Annunzio" Institute for High Culture, Pescara, Italy.
Clin Oral Investig. 2025 Sep 10;29(10):444. doi: 10.1007/s00784-025-06491-2.
This study aimed to compare the efficacy of the full-thickness palatal graft technique (FTPGT) and the coronally advanced flap with subepithelial connective tissue graft (CAF + SCTG) in achieving complete root coverage (CRC) in single gingival recessions (GR).
Forty healthy patients with a single RT1 GR were randomized into two groups: 20 treated with CAF + SCTG and 20 with FTPGT. Baseline and 12-month measurements of GR, keratinized tissue width (KTW), probing depth (PD), clinical attachment level (CAL), and gingival thickness (GT) were recorded. CRC percentage, root coverage percentage (RC%), Root Coverage Esthetic Score (RES), patient-reported outcomes (PROs), and palatal wound healing were evaluated.
At the 12-month evaluation, 19 patients in the FTPGT group achieved CRC compared to 12 in the CAF + SCTG group (p < 0.004). FTPGT showed significantly more GR reduction (0.7 mm ± 0.19), greater CAL gain (0.65 mm ± 0.20), increased GT (0.99 mm ± 0.27), p < 0.001, and KTW gain (2.95 mm ± 0.5), and a higher RC% (12.71 ± 3.82), p < 0.002. PROs did not significantly differ between treatments, nor did palatal healing parameters. CAF + SCTG showed superior RES scores compared to FTPGT (p < 0.0003).
FTPGT is more effective than CAF + SCTG in achieving CRC and improving GT, KTW, CAL gain, and GR reduction, particularly in deep recessions. CAF + SCTG provides superior esthetic outcomes. PROs were comparable between the two techniques, but palatal healing was slower in the FTPGT group.
FTPGT, especially in deep single recessions, could serve as an alternative to CAF + SCTG, as it is associated with greater CRC, greater GT and KTW. However, it is linked to slower healing of the palatal donor site. Clincaltrial.gov registration NCT04028037.
本研究旨在比较全厚腭部移植技术（FTPGT）与冠向推进瓣联合上皮下结缔组织移植术（CAF + SCTG）在实现单发性牙龈退缩（GR）完全牙根覆盖（CRC）方面的疗效。
40例患有单发性RT1 GR的健康患者被随机分为两组：20例接受CAF + SCTG治疗，20例接受FTPGT治疗。记录基线以及12个月时GR、角化组织宽度（KTW）、探诊深度（PD）、临床附着水平（CAL）和牙龈厚度（GT）的测量值。评估CRC百分比、牙根覆盖百分比（RC%）、牙根覆盖美学评分（RES）、患者报告结局（PROs）以及腭部伤口愈合情况。
在12个月评估时，FTPGT组有19例患者实现了CRC，而CAF + SCTG组为12例（p < 0.004）。FTPGT显示GR减少更显著（0.7 mm ± 0.19），CAL增加更多（0.65 mm ± 0.20），GT增加（0.99 mm ± 0.27），p < 0.001，KTW增加（2.95 mm ± 0.5），以及更高的RC%（12.71 ± 3.82），p < 0.002。治疗之间PROs无显著差异，腭部愈合参数也无差异。与FTPGT相比，CAF + SCTG显示出更高的RES评分（p < 0.0003）。
在实现CRC以及改善GT、KTW、CAL增加和GR减少方面，FTPGT比CAF + SCTG更有效，尤其是在深度退缩中。CAF + SCTG提供了更好的美学效果。两种技术的PROs相当，但FTPGT组的腭部愈合较慢。
FTPGT，尤其是在深度单发性退缩中，可作为CAF + SCTG的替代方法，因为它与更大的CRC、更大的GT和KTW相关。然而，它与腭部供区愈合较慢有关。Clinicaltrial.gov注册号NCT04028037。
