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偶然发现的腹腔肿块导致原发性痛风诊断:一例报告

Serendipitous Manifestation of Intra-abdominal Mass Leading to Primary Gout Diagnosis: A Case Report.

作者信息

Iyer Siddhanth S, Seo Su-Hun, Iyer Srinivas

机构信息

Radiology, George Washington University School of Medicine and Health Sciences, Washington D.C., USA.

Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, USA.

出版信息

Cureus. 2025 Aug 10;17(8):e89735. doi: 10.7759/cureus.89735. eCollection 2025 Aug.

DOI:10.7759/cureus.89735
PMID:40932950
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12419490/
Abstract

Gout is characterized by the deposition of monosodium urate (MSU) crystals with negative birefringence under polarized light in synovial fluid and joint regions. This results in the development of chronic inflammatory arthritis, typically in the first metatarsophalangeal, talar, subtalar, ankle, and knee joints. Although less common, an underrecognized feature of gout is extraarticular deposition, such as in the abdomen. This case report describes the presence of a gouty abdominal mass in a 66-year-old male with prior history of gout. We exhibit our imaging findings and discuss the importance of keeping gout in the differential when an unknown abdominal mass is found.

摘要

痛风的特征是在偏振光下,滑液和关节区域出现具有负双折射的尿酸钠(MSU)晶体沉积。这会导致慢性炎症性关节炎的发展,通常累及第一跖趾关节、距骨、距下关节、踝关节和膝关节。虽然不太常见,但痛风一个未得到充分认识的特征是关节外沉积,比如在腹部。本病例报告描述了一名有痛风病史的66岁男性患者出现痛风性腹部肿块的情况。我们展示了影像学检查结果,并讨论了在发现不明腹部肿块时,将痛风纳入鉴别诊断的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb0/12419490/7e0fcd2516ea/cureus-0017-00000089735-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb0/12419490/8b71973d2a4a/cureus-0017-00000089735-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb0/12419490/7e0fcd2516ea/cureus-0017-00000089735-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb0/12419490/8b71973d2a4a/cureus-0017-00000089735-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb0/12419490/7e0fcd2516ea/cureus-0017-00000089735-i02.jpg

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本文引用的文献

1
Global, Regional, and National Prevalence of Gout From 1990 to 2019: Age-Period-Cohort Analysis With Future Burden Prediction.全球、区域和国家痛风患病率(1990-2019 年):基于年龄-时期-队列分析的未来负担预测
JMIR Public Health Surveill. 2023 Jun 7;9:e45943. doi: 10.2196/45943.
2
What Has Dual Energy CT Taught Us About Gout?双能 CT 能告诉我们关于痛风的什么?
Curr Rheumatol Rep. 2021 Jul 14;23(9):71. doi: 10.1007/s11926-021-01035-5.
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Systemic Urate Deposition: An Unrecognized Complication of Gout?全身尿酸沉积:痛风一种未被认识的并发症?
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4
Case Series: Dual-Energy CT in Extra-Articular Manifestations of Gout: Main Teaching Point: Dual-energy CT is a valuable asset in the detection of extra-articular manifestations of gout.病例系列:痛风关节外表现的双能CT:主要要点:双能CT在痛风关节外表现的检测中是一项有价值的工具。
J Belg Soc Radiol. 2020 Jun 3;104(1):27. doi: 10.5334/jbsr.2113.
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Gout.痛风。
Nat Rev Dis Primers. 2019 Sep 26;5(1):69. doi: 10.1038/s41572-019-0115-y.
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Clinical features and recurrent attack in gout patients according to serum urate levels during an acute attack.根据急性发作期间血尿酸水平,痛风患者的临床特征和复发发作情况。
Korean J Intern Med. 2020 Jan;35(1):240-248. doi: 10.3904/kjim.2018.205. Epub 2019 Jan 28.
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Unusual presentation of gouty tophus in the liver with subsequent appearance in the same site of HCC: a correlate diagnosis? Case report.肝脏中痛风石的异常表现,随后在同一部位出现 HCC:相关诊断?病例报告。
World J Surg Oncol. 2019 Jan 8;17(1):10. doi: 10.1186/s12957-018-1546-8.
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Dual-energy CT in gout - A review of current concepts and applications.痛风的双能CT——当前概念与应用综述
J Med Radiat Sci. 2017 Mar;64(1):41-51. doi: 10.1002/jmrs.223. Epub 2017 Feb 26.
9
Diagnosis, treatment, and prevention of gout.痛风的诊断、治疗与预防。
Am Fam Physician. 2014 Dec 15;90(12):831-6.
10
Acute gout attack with normal serum uric acid levels.血清尿酸水平正常的急性痛风发作。
Rev Med Chir Soc Med Nat Iasi. 2014 Oct-Dec;118(4):942-5.